天津医药 ›› 2026, Vol. 54 ›› Issue (8): 891-896.doi: 10.11958/20260447

• 综述 • 上一篇    

脊柱内镜治疗脊柱疾病隐性失血的研究进展

刘阳(), 丁梓华, 刘继琛, 王真()   

  1. 宁夏回族自治区人民医院脊柱与骨肿瘤外科(邮编750002)
  • 收稿日期:2026-02-19 修回日期:2026-05-08 出版日期:2026-08-15 发布日期:2026-08-07
  • 通讯作者: △E-mail:wz2007053@126.com
  • 作者简介:刘阳(2001),男,硕士在读,主要从事脊柱与骨肿瘤外科临床与基础方面研究。E-mail:2845451730@qq.com
  • 基金资助:
    宁夏回族自治区重点研发计划项目(2022BEG03086);自治区重大科技成果转化项目(2022CJE09010)

Research progress of hidden blood loss in spinal diseases treated by spinal endoscopy

LIU Yang(), DING Zihua, LIU Jichen, WANG Zhen()   

  1. Spine and Bone Tumor Surgery, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan 750002, China
  • Received:2026-02-19 Revised:2026-05-08 Published:2026-08-15 Online:2026-08-07
  • Contact: △E-mail: wz2007053@126.com

摘要:

隐性失血(HBL)是指血液渗入组织间隙或因溶血等原因无法被直接观察到的失血,在经皮脊柱内镜(PELD)与单侧双通道内镜(UBE)手术中普遍存在且可对患者术后恢复产生显著负面影响。HBL的发生主要与血液渗入组织间隙及氧自由基介导的溶血相关。脊柱区域Batson椎旁静脉丛的解剖特点、椎体松质骨丰富血运、疏松结缔组织间隙及术中持续灌注液是构成其发生的特异性基础,高龄患者、椎旁肌厚度增加、高体质量指数、糖尿病、高血压、骨质疏松以及融合术式、多节段操作及手术时间延长是其主要影响因素;而氨甲环酸的使用是其重要的保护因素。HBL的防控应贯穿围手术期全程,包括术前识别并管理可控危险因素;术中采用控制性低血压、维持体温正常及合理使用氨甲环酸等措施;术后需动态监测血液学指标,必要时给予输血或补铁治疗。

关键词: 脊柱疾病, 失血, 经皮椎间盘切除术, 单侧双通道内镜

Abstract:

Hidden blood loss (HBL) refers to blood seeping into tissue spaces or blood loss that cannot be directly observed due to causes such as haemolysis. It is common during percutaneous endoscopic lumbar discectomy (PELD) and unilateral bi-lateral endoscopic discectomy (UBE) procedures and can have a significant negative impact on postoperative recovery of patients. The occurrence of HBL is primarily associated with blood seeping into tissue spaces and haemolysis mediated by oxygen-free radicals. The anatomical characteristics of the Batson paravertebral venous plexus in the spinal region, the rich blood supply of the vertebral cancellous bone, the spaces within loose connective tissue and continuous intraoperative perfusion fluid constitute the specific basis for its occurrence. Key influencing factors include advanced age, increased thickness of the paraspinal muscles, high body mass index (BMI), diabetes, hypertension, osteoporosis, as well as fusion procedures, multi-segment operations and prolonged operative time. Whereas the use of tranexamic acid is a key protective factor. The prevention and control of HBL should run through the entire perioperative period, including the preoperative identification and management of modifiable risk factors.The intraoperative measures such as controlled hypotension, maintenance of normal body temperature and the appropriate use of tranexamic acid should be adopted. After the operation, haematological parameters need to be dynamically monitored. Blood transfusion or iron supplementation treatment should be given if necessary.

Key words: spinal diseases, blood loss, percutaneous discectomy, unilateral bi-portal endoscopic discectomy

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