天津医药

• 论著 •    

胃间质瘤患者的胃电活动的初步研究

俞清翔1,陈茉2,王邦茂3,唐方2,常毅湘2   

  1. 1. 天津医科大学总医院消化科
    2.
    3. 天津医科大学总医院
  • 收稿日期:2009-11-17 修回日期:2009-09-25 出版日期:2010-01-15 发布日期:2010-01-15
  • 通讯作者: 王邦茂

The preliminary study on the Gastric Electrical Activity in the Patients with Gastrointestinal Stromal Tumor

  • Received:2009-11-17 Revised:2009-09-25 Published:2010-01-15 Online:2010-01-15

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摘要： 目的：探讨胃间质瘤（GIST）对胃电活动的影响。方法：运用多导胃电图检测27例胃GIST患者（GIST组）及30例健康志愿者（健康对照组）的餐前餐后胃电参数，并进行对比分析。结果：健康对照组餐后各导联较餐前均出现平均频率（MF）、平均振幅（MA）及正常慢波百分比（N%）的增高，差异有统计学意义（P<0.05）， GIST组未出现相应的胃电图改变（P>0.05）2；GIST组各导联餐前MF高于对照组，N%餐前1、3、4导及餐后各导联均低于对照组， T%各导联餐前餐后均高于对照组，MA高于对照组，差异有统计学意义（P<0.05或P<0.01）；GIST组与对照组患者胃动过速发生率分别为66.7%，3.3%，差异有统计学意义（P<0.01）。结论：GIST患者存在餐前餐后胃电活动异常，异常胃电节律以胃动过速为主。

关键词: 胃肠道间质肿瘤, 肌电描记术/方法, 肌电复合波, 移行, 病例对照研究, 禁食, 饭后期间

Abstract: Objects: to explore whether GIST influences the gastric myoelectrical activity. Methods: the EGG parameters of 27 cases of gastric GIST patients (GIST group) and 30 healthy volunteers (control group) were detected by the multi-channel electrogastrogram and were analyzed. Results: Compare with the fasting, the control group postprandial mean frequence (MF), mean amplitude (MA), and normal slow wave percentage (N%) increased, P<0.05. However, those postprandial parameters changes were not found in GIST group, P>0.05. Compared with Control group, the fasting MF and fasting MA increased, the fasting N% of lead 1,3,4 and postprandial N% decreased, both fasting and postprandial T% increased in GIST group, P<0.05 or P<0.01; the tachygastria incidence of GIST group was significantly higher than the controls (66.7% vs 3.3%, P <0.05). Conclusions: The existence of GIST may affect both fasting and postprandial gastric myoelectrical activity. The abnormal gastric electrical rhythm mainly displayed as tachygastria.

Key words: Gastrointestinal stromal tumor, Electromyography/methods, Myoelectric Complex, Migrating, Case-Control Studies, Fasting, Postprandial Period