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冠状动脉内膜剥脱术在冠状动脉搭桥术中的应用研究

王凯   

  1. 天津第一中心医院
  • 收稿日期:2013-11-08 修回日期:2014-02-20 出版日期:2014-08-15 发布日期:2014-08-15
  • 通讯作者: 王凯

Study of Application of Coronary Endarterectomy in Coronary Artery Bypass Graft

Kai WANG   

  1. Department of Cardiovascular Surgery, Tianjin First Center Hospital, Tianjin300192, China
  • Received:2013-11-08 Revised:2014-02-20 Published:2014-08-15 Online:2014-08-15
  • Contact: Kai WANG

摘要: 【摘要】目的  :探讨冠脉内膜剥脱技术(coronary endarterectomy,CE)在慢性闭塞性血管病变的冠脉搭桥手术(coronary artery bypass graft,CABG)中的应用方法,并评估其近中期效果。方法 :研究对象为2009年10月至2012年10月的31例在CABG同时进行CE的患者,在同期行CABG的患者中挑选与研究对象病情相仿的31例患者组成对照组;观察并比较两组患者的术中参数、术后恢复情况和中期随访结果;并总结CE的技术要点。结果:  31例患者共行冠脉内膜剥脱35处,其中左前降支系统13支(37%,其中左前降支6支、对角支7支),回旋支系统3支(8%),右冠状动脉系统19支(54%,其中主干8支、后降支11支);4例患者同时行2支血管内膜剥脱。主动脉阻断时间、体外循环时间、术后恢复情况无显著差异。两组均无围术期心肌梗塞和手术死亡;CE组随访无心绞痛发作,1例患者由于心功能不全并发真菌性肺炎死亡。结论:  CE是CABG的必要的辅助技术,其与单纯CABG相比手术死亡率和主要的并发症发生率没有显著差异,近期和中期效果良好。

关键词: 冠状动脉分流术, 冠脉内膜剥脱术, 冠脉慢性完全闭塞

Abstract: [Abstract] Objective:   To study the application of coronary endarterectomy (CE) in coronary artery bypass graft(CABG) , and to evaluate the effect of CE plus CABG on patients with chronic total occlusion (CTO) combined with diffuse distal atherosclerosis.Methods:   Data from the 31 patients, who underwent coronary endarterectomy in our institution between October 2009 and October 2012, were reviewed retrospectively and compared with a control group of 31 patients matched for age, sex, LV function, and angina class. Results:   27 patients had one, four had two coronary arteries endarterectomized. Of these 35 endarterectomies, 13 (37%) the left anterior descending artery, 3(8%) branches of the circumflex artery, and 19(54%) involved the right coronary artery. There was no myocardial infarctions in the endarterectomy group and control group. All patients were followed up and no recurrent angina in the endarterectomy group. In CE group a patient died of fungal pneumonia and heart failure half a year after operation. Conclusion:   In current cardiac surgical practice, coronary endarterectomy is an indispensable adjunct to CABG. The operative mortality and major morbidity were comparable or similar to coronary artery bypass grafting, and short-term and medium-term results were favorable.

Key words: coronary artery bypass, coronary endarterectomy, chronic total occlusion of coronary artery