天津医药

• 论著 • 上一篇    下一篇

2型糖尿病患者牙周健康状况与血糖、肥胖、血脂的相关性研究

邓嘉胤   

  1. 天津医科大学口腔医院
  • 收稿日期:2010-10-15 修回日期:2010-12-16 出版日期:2011-03-15 发布日期:2011-03-15
  • 通讯作者: 邓嘉胤

Research on the Correlation between Periodontal Health and Blood Glucose, Obesity, and Blood Lipid of Patients with Type 2 Diabetes

  • Received:2010-10-15 Revised:2010-12-16 Published:2011-03-15 Online:2011-03-15

PDF (PC)

2299

摘要： 目的：验证2型糖尿病患者特别是青年组（14-44岁）和老年组（60岁以上）的牙周健康状况与血糖控制、体重指数、血脂水平的相关性。 方法：选取2型糖尿病住院患者229名，分为青年组和老年组进行研究，通过牙周检查、体重指数计算以及糖化血红蛋白、总胆固醇、甘油三酯的住院体检报告单进行数据采集，采用Epdata软件建立数据库，使用SPSS14.0软件包，对数据进行分析。分别验证两年龄组牙周健康状况与血糖控制水平、肥胖、血脂水平的相关性。 结果：总胆固醇（p＜0.001）、糖化血红蛋白（p＜0.001）差异非常显著；而甘油三酯（p =0.016）、超重（p =0.002）、肥胖（p =0.019）差异显著（p＜0.05），以上因素与2型糖尿病患者的牙周病有相关关系。青年组、老年组的多因素Logistic回归分析显示青年组中糖化血红蛋白、甘油三酯、超重、肥胖为2型糖尿病患者牙周病发病的主要危险因素；而老年组中总胆固醇、糖化血红蛋白为2型糖尿病患者牙周病发病的主要危险因素。 结论：在2型糖尿病患者中血糖控制差、肥胖和甘油三酯的升高是青年人群牙周病发病的主要危险因素，而血糖控制和总胆固醇的控制是减少老年人群牙周病发病率的重要措施。

关键词: 2型糖尿病, 牙周炎, 体重指数, 血脂水平

Abstract: Objective：The research is designed to test and verify the correlation between the periodontal health and the control of control, weight index, and lipid level of patients with type II diabetes, during which special attention has been paid on the youth group (aged 14 - 44) and the elderly group (60 years old or above) .Methods：The selected hospitalized patients, in total of 229, were divided into two groups: the youth group (aged 14-44) and the elderly group (60 years old or above). Statistics employed in the research has been collected through the periodontal inspection, body-mass index calculation and hospital medical reports on glycated hemoglobin, total cholesterol, and triglyceride. Afterwards, a database has been established with the help of the software named Epdata. Eventually, the correlation between the periodontal health and glycemic control, weight index, and lipid level of the two groups has been verified based on the data analysis conducted through SPSS14.0 package. Results：Analysis on single factor showed that the difference between total cholesterol p < 0.001) and glycated hemoglobin (p < 0.001) has remarkable statistics meaning. And the differences among of triglycerides (p = 0.016), Overweight (p= 0.002), Obesity (p = 0.019) have statistics meaning. Or in other words, all the above factors were correlated with periodontal disease of the patients with type II diabetes. The logistic regression analysis on both groups showed that glycated hemoglobin ,triglycerides, overweight and obesity are the major reasons for periodontal disease in youth group. While the major reasons for periodontal disease go to the total cholesterol, glycated hemoglobin for the elderly group. Conclusion：As for the young patients with type II diabetes, Poor blood glucose control ,increases in obesity and triglyceride can probably lead up to periodontal disease. While the best prophylactic measure for aging population to reduce the incidence of periodontal disease is to control both blood glucose and total cholesterol.

Key words: Type 2 diabetes, Periodontitis, weight index, Lipid levels.