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光学成像模糊对微扫视性眼球运动影响的研究

史学锋1,许丽敏2,王婷2,赵堪兴2   

  1. 1. 天津医科大学眼科临床学院、天津市眼科医院
    2. 天津医科大学眼科临床学院,天津市眼科医院,天津市眼科研究所,天津市眼科学与视觉科学重点实验室
  • 收稿日期:2011-04-27 修回日期:2011-05-22 出版日期:2011-08-15 发布日期:2011-08-15
  • 通讯作者: 史学锋

Study on the Effect of Optical Imaging Blur on Micro-Saccadic Eye-Movements

  • Received:2011-04-27 Revised:2011-05-22 Published:2011-08-15 Online:2011-08-15
  • Contact: Xue-Feng Shi

摘要: 目的: 比较正常屈光成像和光学成像模糊条件下人眼微扫视性眼球运动的行为学差异,探讨异常视觉经验对微扫视性眼球运动的影响。方法: 2011年1月—3月在天津市眼科医院就诊的屈光矫正正常或无屈光不正的受试者13例。分别在正常屈光成像状态(主导眼为Nd组,非主导眼为Nn组)和增戴-3.00D镜片(主导眼为Bd组,非主导眼为Bn组)条件下进行测试。采用高速眼球运动记录系统对受试者的双眼分别进行注视性眼球运动记录,采用Matlab程序对微扫视性眼球运动成分进行识别、提取和分析。Origin8.0统计软件及Matlab2008统计学工具包对各组微扫视幅度、峰值速度、发生频率、微扫视间隔时间等量化指标进行分析和比较。结果: 各组间平均微扫视幅度差异无统计学意义,Bd组、Bn组峰值速度较Nd组、Nn组显著性降低,Bd组、Bn组微扫视发生频率较Nd组、Nn组明显下降,Bd组、Bn组微扫视间隔时间较Nd组、Nn组明显延长,两种屈光成像状态下主导眼与非主导眼比较差异无统计学意义。结论:高速眼球运动记录对评价视觉质量、研究视觉感知与眼球运动行为之间的关系具有重要临床和科学价值。

关键词: 屈光不正, 成像模糊, 微扫视, 注视, 眼球运动

Abstract: Objective:To compare the differences of behavioural characteristics of human microsaccadic eye-movements between under normal refractive imaging state and optical imaging blur and to explore the the effect of abnormal visual experience on microsaccadic eye-movements. Methods:From January to March in 2011, 13 cases of subjects with corrected normal or normal vision were recruited from the outpatient clinic at Tianjin Eye Hospital.They were tested respectively under normal optical imaging state (group Nd for dorminant eyes and group Nn for non-dorminant eyes) and optical imaing blur state with -3.00D glass (group Bd for dorminant eyes and group Nn for non-dorminant eyes). A high-speed eye-movement recording system was used to monocularly record the fixational eye-movements of subjects'both eyes. A Matlab routine was used to detect and analyze the microsaccadic components of eye-movement waveforms. The microsaccadic amplitudes, peak velocities, occurrence rates, inter-microsaccadic intervals of all groups were analyzed and compared using Origin8.0 and Matlab2008 statistics toolbox. Results:There is no significant difference among mean microsaccadic amplitudes of all groups. The mean peak velocities of groups Bd and Bn was slower than groups Nd and Nn. The mean occurrence rates of groups Bd and Bn was less than groups Nd and Nn. The mean inter-microsaccadic intervals of groups Bd and Bn was longer than gorups Nd and Nn. There is no difference of peak velocity, occurrence rate and inter-microsaccadic interval under two imaging states betwwen dorminant eyes and non-dormiant eyes. Conclusion:High-speed eye-movement recording could provide useful assitance in evaluation of the visual quality and for exploring the relationship between visual perception and eye-movement behaviours.

Key words: ametropia, optical imaging blur, microsaccade, fixation, eye-movement