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子宫特殊类型平滑肌瘤病理诊断的临床实用价值

王岚1,刘易欣2,吴海霞2,谢婉莹2   

  1. 1. 天津市中心妇产科医院
    2. 中心妇产科医院
  • 收稿日期:2012-01-06 修回日期:2012-03-23 出版日期:2012-09-15 发布日期:2012-09-15
  • 通讯作者: 王岚

Clinical Significance of Pathological Diagnosis in Patients with Uterine Leiomyomatosis with Unusual Growth Patterns

  • Received:2012-01-06 Revised:2012-03-23 Published:2012-09-15 Online:2012-09-15

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摘要： 目的：探讨子宫特殊类型（特殊组织学和生长方式）平滑肌瘤病理诊断在临床工作中的实用性。正确解读病理诊断的描述，指导临床医生选择正确术式和治疗。方法：选择研究对象为本院1982-1987年110例子宫特殊类型平滑肌瘤患者为A组；2007-2010年41例同类患者为B组；同期随机选择普通子宫肌瘤41例患者为对照组（C组），随访1～5年，做回顾性分析，对三组病例的年龄、术式、肌瘤复发率和恶变率进行比较。结果：三组间年龄、术式、肌瘤复发无显著差异。三组无1例恶变。结论：子宫特殊类型平滑肌瘤是良性疾病过程。恶性潜能未确定的子宫平滑肌瘤病理诊断应慎重，病理和临床医生应避免认识偏差和过度诊治，术后应严密随访。

关键词: 子宫肌瘤, 病理诊断

Abstract: To investigate the clinical value of pathological diagnosis on uterine leiomyoma with unusual growth patterns (special histology and growth pattern) to guide the appropriate surgical procedures and treatment. Methods: There were three groups in this study. Group A were 110 patients with unusual types of uterine leiomyoma treated in our hospital during 1982 – 1987. Group B were 41 cases with special types of uterine leiomyoma treated in our hospital during 2007 – 2010. Group C were control group included 41 cases of ordinary uterine leiomyoma randomly selected over the same period. The patient age, surgical modes, myoma recurrence rate and malignant transformation rate were retrospectively analyzed and compared between three groups by 1 to 5 years follow-up. Results: There were no significant differences in the patient age, surgical modes and recurrence rate between patients of three groups. No malignant transformation was found in three groups. Conclusion: The special types of uterine leiomyoma have benign manifestations. The pathological diagnosis of undetermined malignant potential uterine leiomyoma should becautious. Pathologist and clinical doctors should avoid understanding deviation and excessive therapy. Close follow-up is needed after surgery.

Key words: myoma, pathologic diagnosis