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代谢综合征与前列腺增生的相关性研究

于春虎,刘忠泽,苏运强,杨春生   

  1. 北京市仁和医院泌尿外科
  • 收稿日期:2013-01-09 修回日期:2013-07-16 出版日期:2013-11-15 发布日期:2013-11-15
  • 通讯作者: 于春虎

Correlation Study of Metabolic Syndrom and Benign Prostatic Hyperplasia

  • Received:2013-01-09 Revised:2013-07-16 Published:2013-11-15 Online:2013-11-15

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摘要：

 【摘要】  目的  探讨代谢综合征（MS）与前列腺增生（BPH）的相关性。  方法  选择经尿道前列腺电切术的127例老年男性患者为研究对象。依据国际糖尿病联盟（IDF2005）诊断标准分为MS组（47例）和非MS组（80例）。记录2组年龄、身高、体质量、血压和体质指数（BMI）以及国际前列腺症状评分（IPSS）。检测空腹血糖（FPG）、总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-C）、前列腺特异抗原（PSA）及最大尿流率（Qmax）。腹部超声测量前列腺纵径、横径及前后径，计算前列腺体积（PV）。  结果 与非MS组相比，MS组的BMI、收缩压、舒张压、FPG、TG、IPSS、PV水平较高，但HDL-C、PSA、Qmax水平较低（均P＜0.05）。  结论  肥胖、高脂血症、糖尿病可能增加BPH发病的概率。

关键词: 前列腺增生, 代谢综合征X, 前列腺体积

Abstract: To explore the relationship between metabolic syndrome (MS) and benign prostatic hyperplasia (BPH) .Methods The patients of TURP from Octobour 2010 to September 2012 in our hospital were devided into two groups according to the definition of MS by IDF in 2005:MS group and without MS group. Data incloud age, body height, body weight, blood pressure, body mass index (BMI) and the international prostate symptom score (IPSS) were record. Fasting plasma glucose (FPG), TG, HDL-C, prostate specific atigen (PSA), prostatic volume (PV) and Qmax were measured and recorded. Results (1) The BMI , systolic blood pressure, diastolic pressure, fasting plasma glucose, triglyceride level were higher, while HDL-C level was lower in MS group than without MS group (all P＜0.005) . (2) The PV and IPSS level were higher, while PSA and Qmax were lower in MS group than without MS group (all P＜0.005) .Conclusions MS could increase IPSS and prostate volume,and reduce PSA. Obesity, hyperlipemia, and diabetes meuitus are risk factors of BPH.