天津医药

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恶性危险指数评价卵巢肿物性质的临床观察

徐曼,瞿全新   

  1. 天津医科大学一中心临床学院
  • 收稿日期:2010-06-08 修回日期:2010-09-07 出版日期:2011-02-15 发布日期:2011-02-15
  • 通讯作者: 徐曼

The clinical investigation of the risk of malignancy index in patients with ovarian masses

  • Received:2010-06-08 Revised:2010-09-07 Published:2011-02-15 Online:2011-02-15
  • Contact: XU MAN

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摘要： 摘要 目的：探讨恶性危险指数对评价卵巢肿物性质的临床价值。方法：选择30例卵巢恶性肿瘤患者及201例卵巢良性肿物患者，根据患者绝经状态、CA125测定、多普勒超声评分计算恶性危险指数(RMI)，分析术前RMI水平和术后病理学诊断结果，计算其对卵巢恶性肿瘤预测的敏感性、特异性、阳性预测值、阴性预测值。结果：RMI对卵巢恶性肿瘤的敏感性、特异性、阳性预测值、阴性预测值分别为：80％，93.5％，64.9％，96.9％。结论：血清CA125联合多普勒超声检查可提高卵巢恶性肿瘤的敏感性和特异性。联合检测有助于早期卵巢恶性肿瘤的发现，利于术前卵巢肿物性质的评价。

关键词: 恶性危险指数, 卵巢肿物, 卵巢恶性肿瘤, CA125, 多普勒超声

Abstract: Abstract ：Objective To explore the clinical value of the risk of malignancy index in patients with ovarian masses. Methods Choosing 30 cases of malignant ovarian tumor patients and 201 cases of benign ovarian tumor patients and computing the risk of malignancy index（RMI）based on serum CA125.menopausal status and ultrasound score. The risk of malignancy index quantity before laparotomy and their pathology after laparotomy were analyzed retrospectively sensitivity，specificity，negative predictive value，positive predictive value was used for calculation.Results The sensitivity and specificity of RMI for ovarian neoplasm was 80％ and 93.5％，respectively its positive predictive value was 64.9％while its negative predictive value was 96.9％。Conclusion The serum of CA125 combined with ultrasound can significantly improve the sensitivity and specificity of malignant ovarian tumor.The combined detection may discover the ovarian neoplasm early and it is good for evaluating the character of the ovarian masses.

Key words: the risk of malignancy index, ovarian masses, ovarian neoplasm, CA125, Doppler ultrasound.