天津医药

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儿童胆汁反流性胃炎与幽门螺杆菌感染的关系

赵煜1,张书红2,刘风林1,李娟1,李妍1   

  1. 1. 天津市儿童医院
    2. 天津市儿童医院消化科
  • 收稿日期:2013-08-07 修回日期:2013-10-15 出版日期:2014-05-15 发布日期:2014-05-15
  • 通讯作者: 赵煜

Correlation between bile reflux gastritis and Helicobacter pylori infection in children

  • Received:2013-08-07 Revised:2013-10-15 Published:2014-05-15 Online:2014-05-15

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摘要： 【摘要】目的 探讨儿童胆汁反流性胃炎(BRG)与幽门螺杆菌(HP)感染之间的关系。方法 258例胆汁反流性胃炎患儿为BRG组,1749例无胆汁反流的胃粘膜炎症患儿为对照组,对两组HP感染率做比较性分析；根据病情分级将胆汁反流性胃炎患儿分为3组，各组间HP感染率做比较性分析；根据胆汁反流分度将胆汁反流性胃炎患儿分为3组，各组间HP感染率做比较性分析。结果 BRG组较对照组HP感染率高，结果有统计学意义，BRG组中不同病情分级组间感染率无统计学意义，BRG组中不同胆汁反流分度组间感染率有统计学意义。结论 在儿童患者中Hp感染是BRG的致病因素之一，随胆汁反流程度的加重，HP感染率增高。

关键词: 胆汁反流性胃炎, 幽门螺杆菌, 病情分级, 反流分度

Abstract: 【Abstract】Objective:To assess the relationships between bile reflux gastritis(BRG) and Helicobacter pylori infection in children. Methods: BRG group include 258 cases of BRG and control group include 1749 cases of mucosal inflammation without bile reflux in children.Underwent a comparative analysis of Helicobacter pylori infection rate on the two groups. According to disease classification in BRG, the 258 cases were divided into three groups and underwent a comparative analysis of Helicobacter pylori infection rate. According to different reflux indexing in BRG, the 258 cases were divided into three groups and underwent a comparative analysis of Helicobacter pylori infection rate. Results: Compared to control group,the infection rate of BRG group were higher. The infection rate of three groups according to different disease classification was not statistically significant. The infection rate of three groups according to reflux indexing was statistically significant. Conclusions: Helicobacter pylori infection is one of the causative factors leading BRG in children.And Helicobacter pylori infection increased the degree of bile refluxing.

Key words: bile reflux gastritis, Helicobacter pylori, disease classification, reflux indexing