天津医药

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氧化亚氮在结肠镜检查中的应用

盛颖玥,俞宪民,刘宗良,薛育政,杨晴,林刚,黄敏娴,殷敏华   

  1. 无锡市第三人民医院
  • 收稿日期:2011-04-22 修回日期:2011-07-07 出版日期:2012-01-15 发布日期:2012-01-15
  • 通讯作者: 薛育政

The application of nitrous oxide in Colonoscopy

  • Received:2011-04-22 Revised:2011-07-07 Published:2012-01-15 Online:2012-01-15

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摘要： 目的： 比较氧化亚氮吸入及丙泊酚静脉麻醉结肠镜检查的临床效果。方法： 103例患者分为2组：丙泊酚静脉全麻组（A组）采用术前丙泊酚静脉注射，笑气组（B组）采用术前笑氧混合吸入，比较观察2组患者血压、脉搏及脉氧饱和度，记录肠镜操作时间，清醒时间及不良反应发生情况。结果： B组复苏清醒时间短于A组，差异有统计学意义（P <0.05）；A、B组患者受检前后血压、脑后等生命体征变化及不适感评价差异无统计学意义（P >0.05）。结论： 笑气吸入与丙泊酚静脉麻醉均能减轻患者结肠镜检查痛苦，但笑气复苏时间明显短于静脉麻醉。

关键词: 氧化亚氮, 丙泊酚, 麻醉和镇痛, 静脉, 结肠镜检查

Abstract: Objective: To compare the effects of nitrous oxide and intravenous anesthesia with propofol in colonoscopy. Methods :103 patients were randomly divided into two groups:the propofol intravenous anesthesia group( group A) and the nitrous oxide group(group B). Observe and compare the blood pressure、pulse oxygen saturation and the performing time of colonoscopy and the time of recovery and the rate of adverse reaction of the two groups. The datas between two groups were compared and statistically analyzed with software SPSS 11.5. Results :group B has shorter recovery time compared with group A,the difference was statistically significant （P<0.05）;the A,B group has no significant difference in vital signs before and after examining and discomfort (P> 0.05). Conclusion: Both nitrous oxide inhaled and propofol intravenous anesthesia can all relieve discomfort in colonoscopy, further more using nitrous oxide has shorter recovery time.

Key words: Nitrous Oxide, Propofol, Anesthesia & Analgesia, Veins, colonoscopy