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4 318例血清标本梅毒HIV检测结果的分析

李韶深1,赵俊芳2,李维云1,刘春莉1,李学斌1,韩玉华1   

  1. 1. 天津市中医药研究院附属医院
    2. 天津市长征医院
  • 收稿日期:2011-08-13 修回日期:2011-11-21 出版日期:2012-08-15 发布日期:2012-08-15
  • 通讯作者: 李韶深

The analysis of HIV and Syphilitic detection results of 4318 serum samples in venereal disease out-patient clinic

  • Received:2011-08-13 Revised:2011-11-21 Published:2012-08-15 Online:2012-08-15

摘要: 摘要 目的 对2010年一个性病门诊实验室梅毒和HIV监测情况进行分析,以期掌握梅毒和HIV流行情况。方法 TPPA和RPR方法同时检测梅毒,HIV使用酶联吸附试验(ELISA)和乳胶层析法检测,计算首诊梅毒阳性的百分率,对所有的血清标本进行HIV检测,并作统计。结果 共检测血清4318例,梅毒首诊3554例,阳性为1168例,梅毒阳性率32.7%,其中男性阳性率16.6%,女性为16.1%。21-30岁的女性阳性率高于男性,其他组别男性高于女性。4318例HIV检测结果,阳性31例,其中女性1例,梅毒检测阴性,男性30例,全部有同性恋史,其中22人合并梅毒阳性,21-30岁感染人数,合并梅毒人数最多,40岁以上的HIV阳性全部合并梅毒感染。结论 经性传播梅毒的阳性率处在较高的水平,可能与多性伴,男男同性恋及无保护的性行为有关,男男同性恋导致男性感染HIV以及HIV和梅毒共感染的几率增加,提示相关部门对不同的易感人群制定相关政策,控制梅毒和HIV的流行趋势。

关键词: 性病门诊, 梅毒, HIV, 男男同性恋

Abstract: Abstract:Objective To master the prevalence condition of HIV and syphilis, the detection status of HIV and syphilis in the laboratory of our hospital’s venereal disease out-patient clinic was analyzed. Methods TPPA and RPR were used to detect syphilis, and positive percentage of first diagnosis was calculated. Meanwhile, ELISA and latex chromatographic analysis test were used to detect anti-HIV antibody of all serum specimens. Results 3554 patients were detected syphilis, the result of 1168 patients was positive (32.7%) .The positive rate of male and female is 16.6% and 16.1% respectively. The positive rate of female is higher than that of male in 21~30 age group ,while male’s positive rate is higher than female’s in other group. 4318 samples were screened anti-HIV antibody, the result of 31 patients was positive, including 1 female whose syphilis result was negative , and 30 male . Among 30 anti-HIV antibody positive male patients, 22 patients were infected by syphilis at the same time, and all patients had homosexuality history. 21-30 group had maximum detected patients and syphilis、HIV infected patients. Discussion The positive rate of syphilis transmitted by sex was in a higher level, which maybe be associated with multiple sexual partners among men who have sex with men (MSM), and unprotected sexual behavior .MSM increase the co-infection rate of syphilis and HIV, which indicate the relative department enact correlated policy for different susceptible population, and control the popular tendency of syphilis and HIV.

Key words: Key worldvenereal disease out-patient clinic, syphilitic, HIV, MSM