天津医药

天津医药 ›› 2020, Vol. 48 ›› Issue (7): 682-688.doi: 10.11958/20200320

• 综述 • 上一篇    

可降解镁基合金骨折固定及骨修复材料的研究进展

姜洪丰1 ，陈民芳2△，刘德宝2   

  1. 1 天津市天津医院脊柱四科（邮编 300211）；2 天津理工大学材料科学与工程学
  • 收稿日期:2020-02-24 修回日期:2020-05-20 出版日期:2020-07-15 发布日期:2020-07-16
  • 作者简介:姜洪丰（1972），男，博士，副主任医师，主要从事脊柱外科相关研究

Research progress of biodegradable magnesium alloys for fracture fixation and bone repair materials

JIANG Hong-feng1 , CHEN Min-fang2△, LIU De-bao2   

  1. 1 The 4th Department of Spine Surgery, Tianjin Hospital, Tianjin 300211, China; 2 School of Materials Science and Engineering, Tianjin University of Technology
  • Received:2020-02-24 Revised:2020-05-20 Published:2020-07-15 Online:2020-07-16

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摘要： 可降解镁基合金材料具有良好的力学性能、突出的生物相容性和成骨诱导性。其作为有临床应用前景的 骨折固定及骨修复替代材料近年来备受关注。本文就可降解医用镁合金材料在骨折固定及骨修复领域的研究进行 总结，分别从镁合金骨折固定及骨修复材料的优势、发展历史、研究及应用现状、存在的问题与挑战等几个方面进行 了综述。

关键词: 骨折固定术, 生物相容性材料, 可降解镁基合金, 骨修复, 成骨诱导性

Abstract: In recent years, biodegradable magnesium-based alloys are showing great potential to be used as a new class of materials and are attracting much attention owing to their characteristics of biodegradation and good osteogenesis inductivity, biocompatibility and other biofunctional properties. These advantages make them promising candidates for fracture fixation and bone repair applications. This paper summarizes the advantages, history, challenges and the recent research progress of biodegradable magnesium-based alloys for orthopedic application.

Key words: fracture fixation, biocompatible materials, biodegradable Mg-based alloy, bone repair, osteogenesis inductivity