天津医药

• 论著 •    

全身18F-FDG PET/CT在原发灶不明的颈部转移性腺癌中的应用价值

郑婧1,高硕2   

  1. 1. 天津医科大学总医院PET中心
    2. 天津医科大学总医院
  • 收稿日期:2009-11-04 修回日期:2009-12-15 出版日期:2010-03-15 发布日期:2010-03-15
  • 通讯作者: 郑婧

Whole Body 18F-FDG PET/CT Imaging for Detection of Primary Tumors in Cervical Metastatic Adenocarcinoma of Unknown Primary Site

ZHENG Jing,硕 高   

  • Received:2009-11-04 Revised:2009-12-15 Published:2010-03-15 Online:2010-03-15
  • Contact: ZHENG Jing

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摘要： 摘要 目的：初步探讨全身18F-FDG PET/CT在原发灶不明的颈淋巴结转移性腺癌中的应用价值。方法：对17例原发灶不明的颈淋巴结转移性腺癌患者行全身PET/CT检查，通过视觉分析和SUV测定对病灶进行判断，所得结果与病理和/或随访结果比较。结果：17例患者中最终明确原发灶13例，其中肺癌8例，结肠癌2例，肾癌、乳腺癌、宫颈癌各1例。4例未发现原发灶患者中，包含3例PET/CT否定原转移性腺癌诊断而诊为恶性淋巴瘤的病例。PET/CT对肿瘤原发灶诊断的灵敏度为92.3%（12/13）、特异性75.0%（3/4）、准确性88.2%（15/17）。另有10例（58.8%）患者除己知转移瘤和原发灶之外，还发现了其他脏器组织的转移。 结论：18F-FDG PET/CT全身显像在探寻颈淋巴结转移性腺癌患者的原发灶及了解病变分布范围方面有重要价值。

关键词: 氟脱氧葡萄糖, 原发肿瘤, 转移性腺癌, 颈部

Abstract: Abstract Objective: To retrospectively evaluate whole body 18F-FDG PET/CT in depicting the primary tomors in cervical metastatic adenocarcinoma of unknown primary site. Methods: Seventeen patients were included and underwent whole body PET/CT imaging. The primary tumors and metastases were detected by visual evaluation and measurements of standardized uptake values.The PET/CT impression was verified by histopathology and/or follow-up. Results: In 17 patienis，primary tumors of 13 patients were confirmed by pathological or clinical follow-up. Among them，8 were in the lung, 1 in breast, 1 in renal, 2 in colon and 1 in cervix. Among the other 4 cases, PET/CT correctly diagnosed 3 cases diagnosed metastatic adenocarcinoma previously but demonstrated as malignant lymphoma finally. The sensitivity, specificity and accuracy of PET/CT in identifying primary tumors were 92.3%, 75.0%, 88.2%, respectively. After PET/CT examination, 10 patients (58.8%) were detected additional metastatic lesions which were missed previously. Conclusion: Whole body 18F-FDG PET/CT may be of relatively higher value in identifying the primary tumor in cervical metastatic adenocarcinoma of unknown primary site. It also may display tumor involvement extent.

Key words: Fluorodeoxyglucose, Primary tumor, Metastatic adenocarcinoma, Cervical