天津医药

• 短篇论著 •    

缺血性脑卒中合并下肢外周动脉疾病的分析

马毓,朱沂   

  1. 新疆自治区人民医院
  • 收稿日期:2009-11-24 修回日期:2010-04-10 出版日期:2010-09-15 发布日期:2010-09-15
  • 通讯作者: 朱沂

The Prevalence of Lower Extremity Peripheral Arterial Disease in Patients with Cerebral Ischemic Stroke

1,   

  • Received:2009-11-24 Revised:2010-04-10 Published:2010-09-15 Online:2010-09-15

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摘要： 【摘要】目的：通过测量踝臂指数评价缺血性脑卒中患者下肢外周动脉疾病的患病情况。 方法：对住院的74例缺血性脑卒中患者进行踝臂指数测量，并进行资料收集和统计学处理。结果：74例缺血性脑卒中患者中有20例合并下肢外周动脉疾病踝臂指数的均值为0.831±0.079）。下肢外周动脉疾病组与非下肢外周动脉疾病组患者相比，糖尿病史（P=0.001）和血浆纤维蛋白原水平（P=0.001）差异有显著性，有统计学意义，而吸烟史（P=0.228）、高血压病史（P=0.359）、血浆C-反应蛋白（P=0.339）和相关血脂指标无统计学意义。结论：通过测量ABI确诊下肢PAD简便易行；缺血性脑卒中患者容易合并下肢外周动脉疾病；缺血性脑卒中合并下肢外周动脉疾病多见于糖尿病和高纤维蛋白原血症患者。

关键词: 踝臂指数, 缺血性脑卒中, 下肢外周动脉疾病

Abstract: 【Abstract】Objective:To access the prevalence of peripheral arterial disease (PAD) in hospitalized patients with cerebral ischemic stroke (CIS) by measuring the ankle-brachial index (ABI). Methods:Chinese patients of cerebral ischemic stroke were invited to participate prior to hospital discharge. Data regarding cerebral ischemic stroke risk factors, history of previous PAD, and ABI were collected. A total of 74 patients (41 men and 33 women) were recruited. Results: 20 patients were found to have PAD (mean ABI =0.831±0.079). There were significant differences in statistics between PAD and non-PAD group in diabetes mellitus(P=0.001) and FIB（P=0.001）.However, there were no significant differences in smoking history (P=0.228)、hypertension (P=0.359)、C-reactive protein (CRP)（P=0.339）、CHOL（P=0.414）、HDLC（P=0.461）、LDLC（P=0.054）、TG（P=0.235） and LP（a）（P=0.252）。Conclusion: Identification of patients with PAD by measuring the ankle-brachial index is easily done. Hospitalized patients with CIS are likely to have concomitant PAD. PAD in patients with CIS is more popular in these patients with advanced diabetic and high Fibrinogen.

Key words: ankle-brachial index, cerebral ischemic stroke, peripheral arterial disease