天津医药 ›› 2020, Vol. 48 ›› Issue (12): 1236-1239.doi: 10.11958/20201067
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李潇，周爽，赵琛
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LI Xiao, ZHOU Shuang, ZHAO Chen
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李潇, 周爽, 赵琛. 长链非编码RNA调控缺血性脑卒中后血管新生的研究进展#br#[J]. 天津医药, 2020, 48(12): 1236-1239.
LI Xiao, ZHOU Shuang, ZHAO Chen. Research progress on the molecular biological mechanism of long non-coding RNA regulating angiogenesis after ischemic stroke[J]. Tianjin Medical Journal, 2020, 48(12): 1236-1239.
摘要： 长链非编码RNA（lncRNA）主要分布在胞核和胞质中，主要调控翻译过程以及蛋白质的靶向运输，比其他非编码RNA种类更多，功能更为复杂。近年来发现lncRNA可能在脑卒中的病理过程中发挥着重要作用。本文对lncRNA调控脑卒中后血管新生方面的研究进展进行综述，以明确lncRNA在缺血性脑卒中血管新生中的作用。
关键词: 卒中, RNA, 长链非编码, 缺血性脑卒中, 血管新生, 综述
Abstract: Long non-coding RNA (lncRNA) is mainly distributed in the nucleus and cytoplasm. It mainly regulates the translation process and targeted transport of proteins. It has more types and more complex functions than other non-coding RNAs. Recent studies have shown that lncRNA may play an important role in the pathological process of stroke. This article reviews the research progress of the molecular biological mechanism of lncRNA regulating angiogenesis after stroke to clarify the role of lncRNA in angiogenesis of ischemic stroke.
Key words: stroke, RNA, long noncoding, ischemic stroke, angiogenesis, review
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链接本文: https://www.tjyybjb.ac.cn/CN/10.11958/20201067
https://www.tjyybjb.ac.cn/CN/Y2020/V48/I12/1236
