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二尖瓣狭窄患者MOSAIC瓣膜置换术后临床疗效评估

杨寅   

  1. 天津市胸科医院
  • 收稿日期:2011-12-09 修回日期:2012-02-07 出版日期:2012-06-15 发布日期:2012-06-15
  • 通讯作者: 杨寅

The clinical performance after mitral valve replacement with MOSAIC for mitral stenosis

Yin YANG   

  • Received:2011-12-09 Revised:2012-02-07 Published:2012-06-15 Online:2012-06-15
  • Contact: Yin YANG

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摘要： 摘要 目的 评估二尖瓣狭窄患者Mosaic瓣膜置换术后左心功能变化及血流动力学表现 方法 2010年1月至2010年12月，我院对33例二尖瓣狭窄患者行Mosaic生物瓣膜置换术，术前与术后3个月、术后1年对患者进行超声随访检查。结果 33例二尖瓣狭窄患者术前与术后1年各项指标差异具有显著性意义，术后左房径、左室舒末径、左室缩末径和肺动脉压力分别为（38.9±5.4）mm、（49.4±5.8）mm、（33.0±5.0）mm和（31.1±5.1）mmHg，明显低于术前（51.7±8.7）mm、（54.5±8.2）mm、（38.5±6.5）mm和（44.3±8.1）mmHg，术后1年最大跨瓣压差（18.4±4.4）mmHg（1 mm Hg = 0. 133 kPa），平均跨瓣压差（6.6±1.3）mmHg，有效瓣口面积（1.9±0.4）cm2，最大跨瓣流速(2.1±0.3)m/s。结论 Mosaic生物瓣置换术后1年具有良好临床疗效。

关键词: Mosaic, 瓣膜置换术, 血流动力学, 生物植入物

Abstract: Abstract Objective: to evaluate the left cardiac function and hemodynamic performance of Mosaic bioprosthesis in mitral valve replacement for mitral stenosis Methods: from January 2010 to December 2010,thirty-three patients underwent mitral valve replacement with Mosaic bioprothesis in hospital. Doppler echocardiograms were recorded before operation 、3 month and 1 year after valve replacement. Result：After operation，left atrium diameter (LAD)[（38.9±5.4）mm vs（51.7±8.7）mm]，left ventricular diastolic diameter(LVDD) [（49.4±5.8）mm vs（54.5±8.2）mm]，left ventricular systolic diameter(LVSD) [（33.0±5.0）mm vs（38.5±6.5）mm]， Pulmonary artery pressure (PAP) [（31.1±5.1）mmHg vs（44.3±8.1）mmHg] were significantly different between preoperation and postoperation at 1 year. Conclusions: The Mosaic bioprosthesis demonstrates excellent clinical performance after 1 year of follow-up.

Key words: Mosaic, valve replacement, hemodynamic, bioprosthesis