天津医药

• 论著 • 上一篇    下一篇

血管回声跟踪技术定量评价吸烟者颈动脉弹性

梁永平1,马琳2   

  1. 1. 河北联合大学（原华北煤炭医学院）附属医院
    2. 唐山华北煤炭医学院附属医院
  • 收稿日期:2011-01-21 修回日期:2011-04-15 出版日期:2011-11-15 发布日期:2011-11-15
  • 通讯作者: 梁永平

The Value of E-Tracking Technology for Evaluating Carotid Artery Elasticity Function in Active Smokers

  • Received:2011-01-21 Revised:2011-04-15 Published:2011-11-15 Online:2011-11-15
  • Contact: YongPing LIANG

PDF (PC)

2052

摘要： 摘要 目的：探讨血管回声跟踪技术（ET）定量评价吸烟者颈动脉血管弹性的意义。方法：选取体检结果正常的男性吸烟者132例，非吸烟者49例（A组）。按吸烟指数将吸烟者分为3组：B组（＜400支年/d）、C组（401～800支年/d）、D组（801～1 200支年/d）。应用ET技术检测各组颈动脉内中膜厚度（IMT）、收缩期血管内径（Ds）和舒张期血管内径（Dd），并计算硬度指数（β）、压力应变弹性系数（Ep）、动脉顺应性（AC）及单点脉搏波传导速度（PWVβ）。结果：对照组及各吸烟组间年龄、体质量指数、心率、收缩压、舒张压、脉压差、IMT、Ds及Dd差异均无统计学意义，4组β、Ep、AC及PWVβ差异有统计学意义（P＜0.01），A组与B组差异无统计学意义，3个吸烟组中任意两组比较差异均有统计学意义（P＜0.05或P＜0.01）。β、Ep及PWVβ均随吸烟指数的增加而增高，而AC随吸烟指数的增加而减低。结论：ET技术能准确获取吸烟者颈动脉弹性参数，在血管发生形态学改变前检测出动脉硬化趋势。

关键词: 超声检查, 血管回声跟踪技术, 吸烟者, 颈动脉, 血管弹性

Abstract: Abstract　Objective：To explore the value of E-tracking technology (ET) in evaluating carotid artery elasticity function in active smokers. Methods：One hundred and thirty-two active smokers and 49 normal nonsmoking persons (group A) were divided into 3 groups by cigarette-smoking index (CSI= the number of cigarette-smoked each day × the year of cigarette smoking), including group B (CSI<400), group C (CSI=401-800) and group D (CSI=801-1200). ET was used to detect the intima media thickness (IMT), internal diameter of systolic (Ds) and internal diameter of diastole (Dd). The values of stiffness parameters (β), pressure-strain elastic modulus (Ep), arterial compliance (AC) and pulse wave conducting velocity (PWVβ) were calculated and analysed in 4 groups. Results：There were no statistical significances in age, body mass index (BMI), heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PD), IMT, Ds, and Dd between group A and other 3 groups. There were significant differences in β, Ep, AC and PWVβ between group A and other 3 groups (P<0.01), except for the group A and group B (P>0.05). And there were significant differences in β, Ep, AC and PWVβ between group B, group C and group D(P＜0.05 or P＜0.01). The values of β, Eρ and PWVβ increased with the increase of CSI, but AC decreased with the increase of CSI. Conclusion: ET technique can be used to access the vessel endothelial dysfunction accurately in active smokers; therefore, the tendency of arteriosclerosis could be detected in early stage.

Key words: Ultrasonography, Carotid arteries, Elasticity, E-tracking technique, Active smoking