血清电解质与冠状动脉病变程度的相关性研究

血清电解质与冠状动脉病变程度的相关性研究

李盈,齐新,刘克强,魏丽萍

天津市人民医院

收稿日期:2011-11-22 修回日期:2012-03-14 出版日期:2012-09-15 发布日期:2012-09-15
通讯作者: 齐新

The Correlation of Serum Electrolytes with Severity of Angiographic Coronary Artery Disease

Received:2011-11-22 Revised:2012-03-14 Published:2012-09-15 Online:2012-09-15

李盈,齐新,刘克强,魏丽萍. 血清电解质与冠状动脉病变程度的相关性研究[J]. .

摘要/Abstract

摘要： 目的：探讨血清电解质钾、钠、氯的水平与冠状动脉病变程度的相关性。方法：将264例疑诊为冠心病且行冠脉造影检查的患者分为冠心病组与非冠心病组，将冠心病组又分为急性心肌梗死（AMI）亚组与非AMI亚组，分析比较各组与亚组间血清电解质钾、钠、氯浓度及其他主要指标的变化，并对所有指标与冠脉病变支数进行相关性分析。结果：冠心病组的血清钾水平高于非冠心病组（P<0.05），血清钠、氯水平低于非冠心病组（P<0.05或P<0.01）。AMI亚组的血清钾水平高于非AMI亚组（P<0.01），血清氯水平低于非AMI亚组（P<0.05），两亚组间血清钠水平差异无统计学意义。相关性分析表明血清钾水平与冠脉病变支数呈正相关（P<0.05），而血清钠、氯水平与其呈负相关（P<0.01）。结论：血清钾水平的升高和血清钠、氯水平的降低与冠状动脉病变程度存在相关性。

关键词: 电解质, 冠状动脉造影, 相关性分析, 急性心肌梗死, 冠脉病变支数

Abstract: Objective: To discuss the relationship between the level of serum electrolytes(K+, Na+, Cl-) and severity of angiographic coronary artery disease. Methods: The study population consisted of 264 patients who underwent coronary angiography for suspected CAD was divided into two groups, the coronary artery disease (CAD) group and the non-CAD group. The CAD group was divided into acute myocardial infarction (AMI) subgroup and non-AMI subgroup. Then to compare the level of serum electrolytes(K+, Na+, Cl-) and other main measurements between two groups and two subgroups. Meanwhile to evaluate the correlation analysis result between all measurements and the number of diseased coronary arteries. Results: The serum potassium level of CAD group was higher than that in non-CAD group (P<0.05), on the contrary, the serum sodium and chlorine concentration of CAD group were both lower than those in another group(P<0.05 or P<0.01). The serum potassium level of AMI subgroup was higher than that in non-AMI subgroup (P<0.01), the serum chlorine concentration of AMI subgroup was lower than that in another subgroup (P<0.05).There was no statistical difference of serum sodium concentration between two subgroups. The correlation analysis indicated that serum potassium level positively correlated with the number of diseased coronary arteries (P<0.05), but sodium and chlorine levels negatively correlated with the number of diseased coronary arteries(P<0.01). Conclusion: Increasing of K+ level and decreasing of Na+ and Cl- levels had correlation with severity of angiographic coronary artery disease.

Key words: electrolytes, coronary angiography, correlation analysis, acute myocardial infarction, the number of diseased coronary arteries

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