急性心肌梗死患者血清胆红素水平改变与近期预后的关系

急性心肌梗死患者血清胆红素水平改变与近期预后的关系

刘娟,齐新

天津市人民医院

收稿日期:2012-03-12 修回日期:2012-09-28 出版日期:2013-02-15 发布日期:2013-02-15
通讯作者: 刘娟

The relationship of the serum bilirubin levels and the clinical adverse eventsin patients with acute myocardial infarction

LIU Juan ¹,QI Xin ²

1. Tianjin Medical University，Tianjin 300070，China；
2.

Received:2012-03-12 Revised:2012-09-28 Published:2013-02-15 Online:2013-02-15
Contact: LIU Juan

刘娟,齐新. 急性心肌梗死患者血清胆红素水平改变与近期预后的关系[J]. .

LIU Juan ¹,QI Xin ². The relationship of the serum bilirubin levels and the clinical adverse eventsin patients with acute myocardial infarction[J]. .

摘要/Abstract

摘要：

【摘要】目的 探讨急性心肌梗死（AMI）患者血清胆红素水平及其与近期预后的关系。方法 109例AMI患者和100例对照组的临床资料，包括年龄、体质量指数、血压、血脂、左室射血分数（LVEF）等，采清晨空腹肘正中静脉血5 mL，测定血清总胆红素(TBIL)、直接胆红素(DBIL)、间接胆红素(IBIL)水平并进行比较。将AMI患者分为不良事件组48例和非事件组61例，比较2组的上述指标。结果 AMI组与对照组相比，性别、年龄、体质量指数、血压、血脂、空腹血糖等临床资料差异无统计学意义（P> 0.05），AMI组总胆红素和间接胆红素低于对照组（P< 0.01），不良事件组血清总胆红素及间接胆红素水平较非事件组显著降低，差异有统计学意义（P< 0.05）。结论血清胆红素水平改变与急性心肌梗死患者的预后有一定的关系。

关键词: 血清胆红素, 急性心肌梗死, 临床不良事件

Abstract:

【Abstract】Objective To evaluate the relationship of the serum bilirubin levels and clinical adverse events in patients with acute myocardial infarction (AMI). Methods Clinical data including age, body mass index, blood pressure, blood lipids and left ventricular ejection fraction (LVEF) of 109 patients with AMI and 100 control subjects were collected and compared. AMI patients were divided into adverse event group (n=48) and non- adverse event group (n=61). The serum total bilirubin (TBIL), direct bilirubin (DBIL) and indirect bilirubin (IBIL) were detected and compared by collecting 5 mL fasting venous blood. Results Compared with the control group, values of body mass index, age, gender，blood pressure，blood lipids， fasting blood sugar and other clinical data showed no significant difference in AMI group (P > 0.05). The serum levels of TBIL and DBIL were significantly lower in AMI group than those of control group (P < 0.01). The total serum bilirubin and indirect bilirubin levels were significantly lower in clinical adverse event group compared with those of non-event group (P < 0.05). Conclusion Changes in serum bilirubin levels have a certain relationship with the clinical adverse events in patients with acute myocardial infarction.

Key words: Serum Bilirubin, Acute Myocardial Infarction, Clinical Adverse Events

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