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间苯三酚在分娩第一产程不同时期给药作用的比较

毛雪梅,刘兆娟   

  1. 天津市南开医院
  • 收稿日期:2011-03-03 修回日期:2011-06-17 出版日期:2011-09-15 发布日期:2011-09-15
  • 通讯作者: 毛雪梅

  • Received:2011-03-03 Revised:2011-06-17 Published:2011-09-15 Online:2011-09-15

摘要: 摘要 目的 观察间苯三酚在分娩第一产程潜伏期和活跃期应用对产程和母婴安全的影响。方法 选择我院待产分娩的足月单胎头位初产妇80例,随机分成观察组和对照组各40例。观察组分别在潜伏期和活跃期给予间苯三酚80mg静脉注射,对照组在活跃期给予间苯三酚80mg静脉注射。结果 观察组潜伏期4.03±0.40h,活跃期5.14±0.76h,宫口扩张平均速度;对照组分别为5.26±0.51h、7.16±0.87h和1.82±1.02 cm/h,两组间有显著性差异(P< 0.01)。结论 潜伏期和活跃期应用间苯三酚对于加速宫颈扩张、缩短产程优于活跃期应用该药,并且对产妇和新生儿无不良影响。

关键词: 间苯三酚, 产程, 潜伏期, 活跃期

Abstract: Abstract Objective:To determine the effects of phloroglucinol in acceleration of labour and its adverse effects on mother and fetus. Methods: A double randomized, controlled trial was conducted on 80 uncomplicated labours, with 40 in study group and 40 in controlled group. The phloroglucinol was given in the study group at the dose of 80mg intravenously in parturient phase and active phase respectively ; and the phloroglucinol was given in the controlled group at the dose of 80mg intravenously in active phase only .Results: The parturient phase was 4.03±0.40h,the active phase was 5.14±0.76h,and the average accelerate rate of cervix dilation was 2.71±1.52cm/h in study group; the results were 5.26±0.51h ,7.16±0.87h and 1.82±1.02cm/h respectively in controlled group. Conclusion: The effect of phloroglucinol given in parturient phase and active phase is superior to active phase only , with regard to acceleration of cervix dilation and reduction of the duration of labor, with no adverse reaction on mothers and fetus.

Key words: Phloroglucinol, Labor duration, Parturient phase, Active phase