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高血压伴左室肥厚患者冠状动脉病变分析

刘志勇   

  1. 天津市胸科医院心内科
  • 收稿日期:2010-08-27 修回日期:2010-12-07 出版日期:2011-05-15 发布日期:2011-05-15
  • 通讯作者: 刘志勇

Analysia of coronary lesion of Left Ventricular Hypertrophy in primary hypertensive patients

  • Received:2010-08-27 Revised:2010-12-07 Published:2011-05-15 Online:2011-05-15

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2007

摘要： 摘要 目的：高血压伴左室肥厚（left ventricular hypertrophy，LVH）患者冠脉病变发生及严重程度分析。方法：553例高血压患者，根据超声心动图的指标，按照是否伴有左室肥厚分为肥厚组（LVH），非肥厚组（N-LVH），比较两组糖尿病、高脂血症、吸烟等危险因素伴发情况及生化指标，分析两组冠脉病变发生及严重程度。结果：与N-LVH组比较，LVH组在性别构成、年龄，合并糖尿病、高脂血症及吸烟等方面，差异无统计学意义（P>0.05）；但高血压病程较长，左室质量及质量指数增加，差异有统计学意义（P<0.01）。两组高血压构成比较，LVH组3级高血压比例较高，而N-LVH组1级、2级高血压比例较高，差异有统计学意义（P<0.01）。LVH组合并冠心病比率76.17%，N-LVH组为62.83%；LVH组双支及3支比率高，N-LVH组冠脉单支病变比率高，两组比较差异有统计学意义（P<0.01）。结论：高血压伴左室肥厚患者高血压病程长，高血压程度严重，冠脉狭窄发生率高且冠脉病变程度更严重。

关键词: 高血压, 左心室肥厚, 冠脉病变

Abstract: Abstract Objective: To study the coronary lesion of Left Ventricular Hypertrophy in primary hypertensive patients. Methods: Five hundred and fifty-three patients with primary hypertensive patients were divided into the left ventricular hypertrophy group(LVH), the non- left ventricular hypertrophy group(N-LVH). They were undergone diagnostic coronary angiography. The risk factors included type2 diabetes mellitus, hyperlipidemia, smoking, etc. Uric acid, Sugar, TC, TG, HDL, LDL were measured. The comparison and analyses was done between the LVH group and the N-LVH group. Results: The hypertensive time and the hypertensive degree of the LVH group are longer and higher than those of the N-LVH group(P<0.01). The occurent rate of coronary stenosis in the LVH group is higher than that of N-LVH group. The ratio of the double-branch group and the three-branch group of LVH group is higher than that of N-LVH group, the ratio of the single-branch group is on the contrary(P<0.01). The prevalence of type2 diabetes mellitus, hyperlipidemia, smoking is similar between them. Conclusion: The occurrent rate of coronary heart disease and the degree of coronary stenosis in the hypertensive patients with LVH are higher and more complicated.

Key words: hypertension, left ventricular hypertrophy, coronary lesion