天津医药

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OSAHS与SYNTAX积分的关系

王明辉1,赵晓赟2,丛洪良3,刘玉洁1,任宁1,李曦铭4   

  1. 1. 天津市胸科医院
    2. 天津市胸科医院胸内科
    3. 天津胸科医院心内科
    4. 天津胸科医院
  • 收稿日期:2012-07-18 修回日期:2012-09-12 出版日期:2013-05-15 发布日期:2013-05-15
  • 通讯作者: 丛洪良

Relation of obstructive sleep apnea hypopnea syndrome with SYNTAX Score

WANG MING HUI1,ZHAO XIAO YUN2,CONG Hong liang1, 1,REN NING1,LI XI MING1   

  1. 1. Tianjin Chest Hospital
    2. Respiratory Department of Tianjin Chest Hospital
  • Received:2012-07-18 Revised:2012-09-12 Published:2013-05-15 Online:2013-05-15
  • Contact: CONG Hong liang

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摘要：

【摘要】 目的  研究阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与SYNTAX积分(SXscore)及冠心病危险因素之间的关系。方法 67例OSAHS患者根据中华医学会呼吸病学分会睡眠呼吸障碍学组的诊断标准,分为轻度组(n=17)、中度组(n=16)、重度组(n=34),完善实验室检查及冠脉造影检查,计算并比较各组SXscore。结果 3组间年龄、性别、体质量、身高、高血压、糖尿病及吸烟者比例比较差异均无统计学意义(P>0.05),肾功能、血脂及超声心动检查中左室舒末内径及射血分数差异亦无统计学意义(P>0.05),SXscore差异有统计学意义(P<0.01),且SXscore随着呼吸暂停低通气指数的升高而增加(rs=0.326,P=0.007)。结论  患者OSAHS严重程度与其冠状动脉病变的严重程度及复杂程度呈正相关,对临床上合并冠心病的OSAHS患者采取再血管化治疗具有一定的参考意义。 

关键词: 阻塞性睡眠呼吸暂停低通气综合征, 经皮冠状动脉介入, 冠脉动脉旁路移植术, SYNTAX积分

Abstract: [Abstract] Objective To investigate the relationship between obstructive sleep apnea syndrome (OSAHS), SYNTAX（SX）score and coronary heart disease risk factors. Methods A total of 67 patients with OSAHS were divided into three groups included mild group (n=17), moderate group (n=16) and severe group (n=34) according to Chinese Society of Respiratory Diseases. The coronary angiography was performed and SXscore was measured in three groups. Results There were no significant differences in age, gender, weight, height, hypertension,and the proportion of smokers and diabetes between three groups (P＞0.05). There were also no significant differences in renal function, blood lipid, left ventricular diastolic diameter and left ventricular ejection fraction between three groups (P＞0.05). There was a significant difference in SXscore between three groups (P <0.01), and which increased with the elevated apnea hypopnea index (rs=0.326，P=0.007). Conclusion There is a positive correlation between the severity of OSAHS and serious and complex coronary artery lesions, which has partly guiding role for OSAHS patients with coronary heart disease taking revascularization therapy.

Key words: Obstructive sleep apnea hypopnea syndrome, Percutaneous transluminal coronary intervention, Coronary artery bypass grafting, SYNTAX Score