天津医药

天津医药 ›› 2016, Vol. 44 ›› Issue (1): 5-8.doi: 10.11958/20150309

• 专题研究呼吸系统疾病 • 上一篇    下一篇

无反应性社区获得性肺炎的诊治进展

李鑫， 曹洁△   

  1. 天津医科大学总医院呼吸与危重症医学科(邮编300052)
  • 收稿日期:2015-10-12 修回日期:2015-11-20 出版日期:2016-01-15 发布日期:2016-01-15
  • 通讯作者: △通讯作者 E-mail: tjcaojie@sina.com E-mail:tjcaojie@sina.com
  • 作者简介:李鑫 （1984）， 女， 硕士， 主要从事呼吸内科方面研究
  • 基金资助:
    国家十二五科技支撑计划 （2012BAI05B02）

Progress in the diagnosis and treatment of non-responding community acquired pneumonia

LI Xin, CAO Jie△   

  1. Abstract： Non-responding pneumonia describes the situation, in which an inadequate clinical response is present de? spite antibiotic treatment. The incidence of treatment failure in community acquired pneumonia (CAP) can range up to 31%. At present, the diagnosis and treatment of this kind of disease remain a great challenge to CAP. For this reason, several stud? ies have attempted to establish risk factors and new strategies for the treatment of non-responding pneumonia. This article re? views the progress of the pathogeny and treatment of non-responding CAP.
  • Received:2015-10-12 Revised:2015-11-20 Published:2016-01-15 Online:2016-01-15
  • Contact: △Corresponding Author E-mail:tjcaojie@sina.com E-mail:tjcaojie@sina.com
  • About author:Department of Respiratory Medicine, General Hospital of Tianjin Medical University, Tianjin 300052, China

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摘要： 摘要： 无反应性社区获得性肺炎 （CAP） 是指患者接受初始感染治疗后， 病情无好转或恶化， 其在 CAP 中的比例可达到 30%。目前， 对这类患者的诊断和治疗仍为 CAP 的难点。有关研究试图确定这部分患者的高危因素， 并提出进一步诊治方案。本文对目前无反应性 CAP 的病因和诊治进展进行综述。

关键词: 无反应性肺炎, 社区获得性肺炎, 治疗失败, 生物学标志物, 经验性治疗

Abstract: Abstract： Non-responding pneumonia describes the situation, in which an inadequate clinical response is present de⁃ spite antibiotic treatment. The incidence of treatment failure in community acquired pneumonia (CAP) can range up to 31%. At present, the diagnosis and treatment of this kind of disease remain a great challenge to CAP. For this reason, several stud⁃ ies have attempted to establish risk factors and new strategies for the treatment of non-responding pneumonia. This article re⁃ views the progress of the pathogeny and treatment of non-responding CAP.

Key words: non-responding pneumonia;, community acquired pneumonia;, treatment failure;, biomarkers, empiric treatment