天津医药

天津医药 ›› 2017, Vol. 45 ›› Issue (10): 1076-1079.doi: 10.11958/20170563

• 临床研究 • 上一篇    下一篇

慢性阻塞性肺疾病患者稳定期不合理用药情况分析

邱水晶 1，陈丽娟 1△，马辉 2，张永祥 2，赵芳 2，李广生 2，潘建峰 2   

  1. 1 天津市胸科医院药剂科（邮编 300222），2 呼吸与危重症医学科
  • 收稿日期:2017-05-12 修回日期:2017-08-23 出版日期:2017-10-15 发布日期:2017-10-13
  • 通讯作者: 邱水晶 E-mail:qiushuijing2652@163.com
  • 作者简介:邱水晶（1985），女，主管药师，硕士，主要从事呼吸系统疾病用药相关研究

Analysis of irrational drug use in patients with stable chronic obstructive pulmonary disease

QIU Shui-jing1, CHEN Li-juan1△, MA Hui2, ZHANG Yong-xiang2, ZHAO Fang2, LI Guang-sheng2, PAN Jian-feng2   

  1. 1 Department of Pharmacy, 2 Department of Respiratory and Critical Care Medicine, Tianjin Chest Hospital, Tianjin 300222, China
  • Received:2017-05-12 Revised:2017-08-23 Published:2017-10-15 Online:2017-10-13

PDF (PC)

3735

摘要： 目的 了解我院慢性阻塞性肺疾病（COPD）患者稳定期的规范用药情况，为合理用药提供参考。方法 选取 2016 年 6 月—2017 年 1 月我院收治的 COPD 患者共 157 例。其中包括轻度 3 例，中度 18 例，重度 39 例，极重 度 97 例。采用自制的用药调查表，了解患者的基本情况、合并症以及不合理用药情况。结果 重度以上的 COPD 患者以男性为主，多合并高血压和心血管疾病。157 例患者中，有 12 例中度 COPD 患者应用吸入性糖皮质激素/支 气管扩张剂，45 例合并肺心病患者使用甲氧那明复合剂，26 例患者使用白三烯受体抑制剂；14 例患者无明显感染指 征使用抗感染治疗药物，11 例患者稳定期应用过系统性糖皮质激素治疗，均为不合理用药。结论 部分稳定期 COPD 患者存在不合理用药情况，医务人员应严格掌握适应证，加强患者用药教育，指导合理用药，避免不良后果的发生。

关键词: 肺疾病, 慢性阻塞性, 稳定期, 合理用药

Abstract: Objective To investigate the standard prescription in patients with stable chronic obstructive pulmonary disease (COPD) and to provide a reference for rational drug use. Methods A total of 157 patients with COPD in our hospital were included into the study from June 2016 to January 2017. Of patients, there were 3 patients with mild airflow limitation, 18 patients with moderate airflow limitation, 39 patients with severe airflow limitation and 97 patients with extremely severe airflow limitation. The self-made questionnaire was used to understand the basic situation, complications and irrational drug use. Results Most severe and extremely severe COPD patients were male, and most of them combined with high blood pressure and cardiovascular disease. Of the 157 patients, 12 cases with moderate airflow limitation used inhaled therapy of corticosteroids/bronchodilator medications, 45 cases combined with pneumocardial disease used compound methoxyphenamine, 26 cases used leukotriene receptor antagonist, 14 cases used antibiotics for no obvious infection symptom and 11 cases used systemic corticosteroids in stable COPD. All of them belong to rational drug use. Conclusion There are some unreasonable situations of drug using in patients with stable COPD. The medical staff should strictly control indications, strengthen the education for drug use, guide rational drug use and avoid the occurrence of adverse consequences.

Key words: pulmonary disease, chronic obstructive, stable phase, rational drug use