天津医药 ›› 2018, Vol. 46 ›› Issue (12): 1324-1326.doi: 10.11958/20180695

• 临床研究 • 上一篇    下一篇

莫沙必利致嗜酸性粒细胞增多一例

齐洪武,赵彩霞,刘岩松   

  1. 1中国人民解放军白求恩国际和平医院神经外科(邮编050082),2药剂科
  • 收稿日期:2018-05-02 修回日期:2018-10-31 出版日期:2018-12-15 发布日期:2019-01-24
  • 通讯作者: 齐洪武 E-mail:827104781@qq.com

One case of eosinophilia caused by mosapride

QI Hong-wu,ZHAO Cai-xia,LIU Yan-song   

  1. 1 Department of Neurosurgery, 2 Department of Pharmacy, Bethune International Peace Hospital of Chinese People’s Liberation Army, Shijiazhuang, Hebei 050082, China
  • Received:2018-05-02 Revised:2018-10-31 Published:2018-12-15 Online:2019-01-24
  • Contact: Hong-Wu QI E-mail:827104781@qq.com

摘要: 莫沙必利作为消化道促动力药物,不良反应发生率低,尤其应用后出现嗜酸性粒细胞增多的报道极为罕见。本文报告1例我院收治的脑干出血恢复期患者鼻饲枸橼酸莫沙必利分散片溶解液后出现嗜酸性粒细胞增多,经停该药及抗过敏治疗后痊愈出院。莫沙必利作为临床常用药物,在使用时如出现嗜酸性粒细胞增多,应警惕药物不良反应可能,妥善处理。

关键词: 消化不良, 嗜酸粒细胞增多, 莫沙必利

Abstract: Mosapride, as a gastroprokinetic agent, has a low incidence of adverse reactions, especially the reports of eosinophilia are extremely rare. A case of convalescent brainstem hemorrhage in our hospital was reported. After nasal feeding of mosapride citrate dispersible tablets, eosinophils increased. The patient was cured and discharged after treatment with antianaphylaxis and discontinuation of mosapride. As a common clinical drug, mosapride should be alert to the possibility of drug allergy reaction if eosinophilia occurs.

Key words: dyspepsia, eosinophilia, mosapride