氢吗啡酮复合罗哌卡因骶管阻滞在儿童尿道下裂手术中的应用效果

doi:10.11958/20221210

天津医药 ›› 2023, Vol. 51 ›› Issue (3): 274-276.doi: 10.11958/20221210

氢吗啡酮复合罗哌卡因骶管阻滞在儿童尿道下裂手术中的应用效果

张萌¹(), 覃道锐², 杨博², 谢敏¹, 刘云飞¹, 苏鹏^△()

1 四川省医学科学院·四川省人民医院麻醉科（邮编610072）
2 小儿外科, 四川省人民医院麻醉科（邮编610072）

收稿日期:2022-08-01 修回日期:2022-10-12 出版日期:2023-03-15 发布日期:2023-03-02
通讯作者: 苏鹏 E-mail:3320653788@qq.com;532161600@qq.com
作者简介:张萌（1990），女，主治医师，主要从事小儿麻醉方面研究。E-mail：3320653788@qq.com
基金资助:
国家自然科学基金青年基金(82101666)

The utilization of ropivacaine combined with hydromorphone in caudal block for children undergoing hypospadias surgery

ZHANG Meng¹(), QIN Daorui², YANG Bo², XIE Min¹, LIU Yunfei¹, SU Peng^△()

1 Department of Anesthesiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, China
2 Department of Pediatric Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, China

Received:2022-08-01 Revised:2022-10-12 Published:2023-03-15 Online:2023-03-02
Contact: SU Peng E-mail:3320653788@qq.com;532161600@qq.com

张萌, 覃道锐, 杨博, 谢敏, 刘云飞, 苏鹏. 氢吗啡酮复合罗哌卡因骶管阻滞在儿童尿道下裂手术中的应用效果[J]. 天津医药, 2023, 51(3): 274-276.

ZHANG Meng, QIN Daorui, YANG Bo, XIE Min, LIU Yunfei, SU Peng. The utilization of ropivacaine combined with hydromorphone in caudal block for children undergoing hypospadias surgery[J]. Tianjin Medical Journal, 2023, 51(3): 274-276.

摘要/Abstract

摘要： Objective To evaluate the efficacy and safety of ropivacaine combined with hydromorphone in caudal block for children undergoing hypospadias surgery. Methods A total of 110 male children aged 0-4 years old who underwent hypospadias surgery were randomly divided into the R group (received caudal block with 0.2% ropivacaine 1 mL/kg) and the HR group (received caudal block with 0.2% ropivacaine 1 mL/kg and hydromorphone 10 μg/kg) with 55 children for each group. Anesthesia time, operation time, postoperative Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) pain scores and complications were recorded and compared between the two groups. Results Compared with the R group, the duration of analgesia time was longer in the HR group (P<0.05), and the 12 h and 18 h CHEOPS pain scores after surgery were lower in the HR group (P<0.05). There were no significant differences in the postoperative complications between the two groups (P>0.05). Conclusion The utilization of ropivacaine combined with hydromorphone in caudal block is safe and effective in children undergoing hypospadias surgery. This method could significantly prolong analgesic time of caudal block and improve the postoperative recovery quality.

关键词: 氢吗啡酮, 罗哌卡因, 尿道下裂, 儿童, 骶管阻滞

Key words: hydromorphone, ropivacaine, hypospadias, child, caudal block

中图分类号:

R614

图/表 4

参考文献 16

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组别	年龄（岁）	身高（cm）	体质量（kg）
R组	1.95±0.73	88.96±7.27	12.63±2.17
HR组	1.84±0.76	88.85±9.28	12.69±2.41
t	0.765	0.069	1.018

组别	年龄（岁）	身高（cm）	体质量（kg）
R组	1.95±0.73	88.96±7.27	12.63±2.17
HR组	1.84±0.76	88.85±9.28	12.69±2.41
t	0.765	0.069	1.018

组别	1 h	6 h	12 h	18 h	24 h
R组	4.9±0.6	5.8±0.7	7.1±0.8	8.1±0.8	6.9±0.6
HR组	4.8±0.6	5.5±0.8	6.0±0.7	7.3±0.8	6.8±0.7
t	1.110	1.422	7.183^＊＊	5.920^＊＊	1.189

组别	1 h	6 h	12 h	18 h	24 h
R组	4.9±0.6	5.8±0.7	7.1±0.8	8.1±0.8	6.9±0.6
HR组	4.8±0.6	5.5±0.8	6.0±0.7	7.3±0.8	6.8±0.7
t	1.110	1.422	7.183^＊＊	5.920^＊＊	1.189

组别	手术时间（min）	麻醉时间（min）	苏醒时间（min）
R组	133.2±54.6	183.8±54.5	12（8，18）
HR组	129.7±64.5	178.9±72.8	10（10，12）
t或Z	0.305	0.400	1.812

氢吗啡酮复合罗哌卡因骶管阻滞在儿童尿道下裂手术中的应用效果

The utilization of ropivacaine combined with hydromorphone in caudal block for children undergoing hypospadias surgery

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组别	恶心呕吐	低氧血症	呼吸抑制/暂停	瘙痒	支气管痉挛	喉痉挛	住院时间（d）
R组	4（7.3）	6（7.3）	2（3.6）	0	0	0	11.2±1.6
HR组	6（10.9）	7（9.1）	3（5.5）	2（3.6）	0	0	11.4±2.1
χ²、P或t	0.440	0.087	0.210	0.495^△	-	-	0.664

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