慢性疼痛患者脑电时间-频率信号变化研究进展

doi:10.11958/20241120

天津医药 ›› 2024, Vol. 52 ›› Issue (12): 1340-1344.doi: 10.11958/20241120

• 综述 • 上一篇

慢性疼痛患者脑电时间-频率信号变化研究进展

丁宁¹(), 李亚杰¹, 刘敏琦¹, 李奇², 邢政², 褚晓蕾², 徐卫国²^,^△()

1 天津体育学院运动健康学院（邮编301617）
2 天津大学天津医院创伤骨科

收稿日期:2024-08-16 修回日期:2024-09-26 出版日期:2024-12-15 发布日期:2024-12-17
通讯作者: △E-mail：13702172721@163.com
作者简介:丁宁（1990），男，硕士在读，主要从事慢性疼痛的评估与治疗研究。E-mail：dn2967194838@163.com
基金资助:
国家重点研发计划“生物与信息融合（BT与IT融合）”重点专项(2023YFF1205200);天津市自然科学基金面上项目(22JCYBJC00210);天津市自然科学基金面上项目(22JCYBIC00220)

Research progress on changes in EEG time-frequency signals in patients with chronic pain

DING Ning¹(), LI Yajie¹, LIU Minqi¹, LI Qi², XING Zheng², CHU Xiaolei², XU Weiguo²^,^△()

1 College of Exercise & Health, Tianjin University of Sport, Tianjin 301617, China
2 Department of Orthopaedic Trauma, Tianjin Hospital, Tianjin University

Received:2024-08-16 Revised:2024-09-26 Published:2024-12-15 Online:2024-12-17
Contact: △E-mail：13702172721@163.com

丁宁, 李亚杰, 刘敏琦, 李奇, 邢政, 褚晓蕾, 徐卫国. 慢性疼痛患者脑电时间-频率信号变化研究进展[J]. 天津医药, 2024, 52(12): 1340-1344.

DING Ning, LI Yajie, LIU Minqi, LI Qi, XING Zheng, CHU Xiaolei, XU Weiguo. Research progress on changes in EEG time-frequency signals in patients with chronic pain[J]. Tianjin Medical Journal, 2024, 52(12): 1340-1344.

摘要/Abstract

摘要：

慢性疼痛是一种主观感受，难以进行准确的客观评估。脑电图（EEG）能够监测患者大脑生理电信号，时间信号能够反映处理任务时的大脑活动，频率信号可以反映安静状态时的大脑活动。该文综述了慢性疼痛患者脑电时间信号中事件相关电位变化情况、频率信号中不同频段变化情况以及两种信号之间事件相关同步或去同步现象变化情况。

关键词: 慢性疼痛, 脑电描记术, 事件相关电位, 脑电波

Abstract:

Chronic pain is a subjective experience that is difficult to accurately and objectively assess. Electroencephalography (EEG) can record physiological electrical signals generated during brain activity, and time signals reflect brain activity during task processing. The frequency signals reflect quiet brain activity. This paper reviews changes of event-related potential in EEG time signal, changes of different frequency bands in frequency signal and changes of event-related synchronization or desynchronization between the two signals in patients with chronic pain.

Key words: chronic pain, electroencephalography, event-related potentials, brain waves

中图分类号:

R441.1

图/表 1

参考文献 42

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频段	频率范围/Hz	变化情况
δ	0.5~3.5	总体表现为活跃状态
θ	4~7	总体表现为活跃状态，且集中在大脑额区、中央区
α	8~13	具体变化结论不一致，但大多表现为减弱状态
β	14~30	总体表现为活跃状态，主要集中在额区、中央区，变化表现与疼痛强度有关
γ	>30	表现为活跃状态

频段	频率范围/Hz	变化情况
δ	0.5~3.5	总体表现为活跃状态
θ	4~7	总体表现为活跃状态，且集中在大脑额区、中央区
α	8~13	具体变化结论不一致，但大多表现为减弱状态
β	14~30	总体表现为活跃状态，主要集中在额区、中央区，变化表现与疼痛强度有关
γ	>30	表现为活跃状态

慢性疼痛患者脑电时间-频率信号变化研究进展

Research progress on changes in EEG time-frequency signals in patients with chronic pain

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