完全植入式静脉输液港非计划性取出后再植的可行性分析

doi:10.11958/20253701

天津医药 ›› 2026, Vol. 54 ›› Issue (5): 513-516.doi: 10.11958/20253701

完全植入式静脉输液港非计划性取出后再植的可行性分析

王欣怡(), 穆宁, 李凤娥, 刘梅, 徐悦, 吴盛楠, 马春华^△()

天津市人民医院（南开大学第一附属医院）肿瘤五科（邮编 300121

收稿日期:2025-12-20 修回日期:2026-02-11 出版日期:2026-05-15 发布日期:2026-05-13
通讯作者: ^△E-mail：mch8178@163.com
作者简介:王欣怡（1999），女，医师，主要从事多种恶性肿瘤的综合治疗方面研究。E-mail：2832267890@qq.com
基金资助:
中国健康促进基金会科研课题基金资助项目(2019ZGJCJJLM)

Feasibility analysis of reimplantation after unplanned removal of totally implantable venous access ports

WANG Xinyi(), MU Ning, LI Feng’e, LIU Mei, XU Yue, WU Shengnan, MA Chunhua^△()

Department of Oncology Ⅴ, Tianjin Union Medical Center (The First Affiliated Hospital of Nankai University), Tianjin 300121, China

Received:2025-12-20 Revised:2026-02-11 Published:2026-05-15 Online:2026-05-13
Contact: ^△E-mail：mch8178@163.com

王欣怡, 穆宁, 李凤娥, 刘梅, 徐悦, 吴盛楠, 马春华. 完全植入式静脉输液港非计划性取出后再植的可行性分析[J]. 天津医药, 2026, 54(5): 513-516.

WANG Xinyi, MU Ning, LI Feng’e, LIU Mei, XU Yue, WU Shengnan, MA Chunhua. Feasibility analysis of reimplantation after unplanned removal of totally implantable venous access ports[J]. Tianjin Medical Journal, 2026, 54(5): 513-516.

摘要/Abstract

摘要：

目的探讨完全植入式静脉输液港（TIVAP）再植术处理非计划性取港事件的可行性、安全性及适用人群。方法回顾性收集10例接受TIVAP功能障碍需非计划性取港患者的临床资料，评估TIVAP再植术的技术成功率、术后并发症及随访结局。结果 10例患者在非计划性取港事件发生后,于数字减影血管造影（DSA）引导下顺利完成TIVAP再植，技术成功率为100%。随访截至2025年11月30日，中位随访271 d，8例未再发生TIVAP相关并发症并顺利完成治疗，2例分别因囊袋再次破裂致港体外露及切口长期不愈而提前取港。全组未见感染、药物外渗等严重不良事件。结论 TIVAP再植术可作为部分非计划性取港事件的有效补救手段，能够快速恢复输液港功能，具有一定安全性和经济性。

关键词: 完全植入式静脉输液港, 导管末端移位, 导管堵塞, 港体外露, 输液港再植术

Abstract:

Objective To evaluate the feasibility, safety and appropriate patient selection for re-implantation of totally implantable venous access ports (TIVAPs) after unplanned port removal. Methods Clinical data from 10 patients who required unplanned port removal due to TIVAP dysfunction were retrospectively collected to evaluate the technical success rate, postoperative complications and follow-up outcomes of TIVAP reimplantation. Results Ten patients underwent TIVAP re-implantation under digital subtraction angiography (DSA) guidance following unplanned port removal, with a technical success rate of 100%. By the end of follow-up on 30 November 2025, the median follow-up duration was 271 days. Eight patients experienced no further TIVAP-related complications and successfully completed their planned treatments, while two patients required premature port removal due to recurrent pocket rupture with port exposure and persistent wound non-healing, respectively. There were no infection, drug extravasation or other serious adverse events in the intire group. Conclusion TIVAP reimplantation may serve as an effective remedial strategy for selected cases of unplanned port removal, with acceptable safety and economic value.

Key words: totally implantable venous access port, catheter displacement, catheter occlusion, port exposure, port reimplantation

中图分类号:

R472

图/表 2

参考文献 20

[1]	MANIK YUNIAWATY WETAN N, IRAWAN H, ADIPUTRA P. Spontaneous catheter tip migration in totally implantable venous access port(TIVAP) to right atrium[J]. Int J Surg Case Rep, 2024, 123:110122. doi:10.1016/j.ijscr.2024.110122.
[2]	ZHOU Y, LAN Y, ZHANG Q, et al. Totally implantable venous access ports:a systematic review and meta-analysis comparing subclavian and internal jugular vein punctures[J]. Phlebology, 2022, 37(4):279-288. doi:10.1177/02683555211069772.
[3]	HUANG X M, LI X, DENG J, et al. Clinical applications and research progress of totally implantable venous access ports:a literature review[J]. Front Oncol, 2024, 14:1519728. doi:10.3389/fonc.2024.1519728.
[4]	D'SOUZA P C, KUMAR S, KAKARIA A, et al. Complications and management of totally implantable central venous access ports in cancer patients at a university hospital in oman[J]. Sultan Qaboos Univ Med J, 2021, 21(1):e103-e109. doi:10.18295/squmj.2021.21.01.014.
[5]	中国中西医结合学会外周血管疾病委员会中心静脉通路专家组. 静脉输液港植入与管理多学科专家共识(2023版)[J]. 中国普通外科杂志, 2023, 32(6):799-814.
	The Central Venous Access Expert Group of the Peripheral Vascular Disease Committee of the Chinese Society of Integrated Traditional Chinese and Western Medicine, et al. Multidisciplinary expert consensus on implantation and management of venous infusion port (2023 edition)[J]. China Journal of General Surgery, 2023, 32(6):799-814. doi:10.7659/j.issn.1005-6947.2023.06.001.
[6]	张晓玲, 高远, 刘春梓, 等. 完全植入式输液港维护及并发症处置专家共识[J]. 中华医院感染学杂志, 2023, 33(16):2401-2404.
	ZHANG X L, GAO Y, LIU C Z, et al. Expert consensus on maintenance and complication management of fully implanted infusion ports[J]. Chinese Journal of Nosocomiology, 2023, 33(16):2401-2404. doi:10.11816/cn.ni.2023-230332.
[7]	中国医师协会介入医师分会介入围手术学组. 植入式静脉给药装置护理管理专家共识[J]. 介入放射学杂志, 2023, 32(4):305-312.
	Interventional Perioperative Group of the Interventional Physicians Branch of the Chinese Medical Doctor Association. Expert consensus on nursing management of totally implantable venous access device[J]. Journal of Interventional Radiology, 2023, 32(4):305-312. doi:10.3969/j.issn.1008-794X.2023.04.001.
[8]	ZHANG Y, ZHAO R, JIANG N, et al. A retrospective observational study on maintenance and complications of totally implantable venous access ports in 563 patients:prolonged versus short flushing intervals[J]. Int J Nurs Sci, 2021, 8(3):252-256. doi:10.1016/j.ijnss.2021.05.005.
[9]	KEHAGIAS E, GALANAKIS N, TSETIS D. Central venous catheters:which,when and how[J]. Br J Radiol, 2023, 96(1151):20220894. doi:10.1259/bjr.20220894.
[10]	THIEL K, KALMBACH S, MAIER G, et al. Standardized procedure prevents perioperative and early complications in totally implantable venous-access ports-a complication analysis of more than 1000 TIVAP implantations[J]. Langenbecks Arch Surg, 2022, 407(8):3755-3762. doi:10.1007/s00423-022-02656-9.
[11]	TSURUTA S, GOTO Y, MIYAKE H, et al. Late complications associated with totally implantable venous access port implantation via the internal jugular vein[J]. Support Care Cancer, 2020, 28(6):2761-2768. doi:10.1007/s00520-019-05122-3.
[12]	OLIVA B, AMARNEH M A. Safety and effectiveness of fibrin sheath stripping of pediatric chest ports[J]. J Vasc Interv Radiol, 2024, 35(5):759-766. doi:10.1016/j.jvir.2024.01.011.
[13]	杜洪涛, 邵国庆, 李瑞红, 等. 静脉输液港并发纤维蛋白鞘一例[J]. 中华介入放射学电子杂志, 2016, 4(1):51-52.
	DU H T, SHAO G Q, LI R H, et al. A case of fibrin sheath complicating an intravenous infusion port[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2016, 4(1):51-52. doi:10.3877/cma.j.issn.2095-5782.2016.01.014.
[14]	LIU W, HAN Q, LI L, et al. Catheter malposition analysis of totally implantable venous access port in breast cancer patients[J]. Front Surg, 2022, 9:1061826. doi:10.3389/fsurg.2022.1061826.
[15]	WANG Y C, LIN P L, CHOU W H, et al. Long-term outcomes of totally implantable venous access devices[J]. Support Care Cancer, 2017, 25(7):2049-2054. doi:10.1007/s00520-017-3592-0.
[16]	潘天帆, 高峰, 任冬青, 等. 完全植入式输液港植入术后导管头端异位介入复位6例[J]. 介入放射学杂志, 2023, 32(3):251-254.
	PAN T F, GAO F, REN D Q, et al. Interventional restoration for malposition of catheter tip after the placement of totally implantable access port:preliminary results in 6 cases[J]. Journal of Interventional Radiology, 2023, 32(3):251-254. doi:10.3969/j.issn.1008-794X.2023.03.011.
[17]	TASHI S, TAN A B, CHUA J, et al. Radiologic placement of totally implantable venous access devices:outcomes and complications from a large oncology cohort[J]. Ann Acad Med Singap, 2024, 54(1):27-35. doi:10.47102/annals-acadmedsg.2024166.
[18]	王学焕, 马春华, 刘梅. 磺胺嘧啶银乳膏治疗1例静脉输液港港座外露患者的护理体会[J]. 中华全科医学, 2024, 22(7):1264-1266.
	WANG X H, MA C H, LIU M. Nursing experience of silver sulfadiazine cream in the treatment of a patient with exposure of intravenous infusion port[J]. Chinese Journal of General Practice, 2024, 22(7):1264-1266. doi:10.16766/j.cnki.issn.1674-4152.003613.
[19]	LIU C, LIU X, ZHAO S, et al. Port-exposure management of totally implantable venous access ports: a case report[J]. J Cancer Res Ther, 2023, 19(4):1064-1069. doi:10.4103/jcrt.jcrt_666_23.
[20]	管玉婷, 黄丽, 陈建平, 等. 输液港囊袋修正术处理输液港外露的临床疗效分析[J]. 岭南现代临床外科, 2021, 21(1):130-133.
	GUAN Y T, HUANG L, CHEN J P, et al. Analysis of the clinical effect of bag correction of infusion port in the treatment of exposure of infusion port[J]. Lingnan Modern Clinics in Surgery, 2021, 21(1):130-133. doi:10.3969/j.issn.1009-976X.2021.01.025.

患者	性别	年龄/岁	BMI/（kg/m²）	导管头端位置	并发症类型	随访时间/d	结局	远期结局
1	男	63	25.9	T6下缘	港体外露	763	失败	囊袋再次破裂，取出TIVAP
2	男	73	26.1	T7上缘	港体外露	337	成功	完成治疗
3	女	57	25.7	T6下缘	港体外露	281	成功	完成治疗
4	男	74	18.6	T6下缘	港体外露	557	成功	完成治疗
5	女	65	20.4	T6下缘	导管贴壁	181	成功	完成治疗
6	男	64	25.0	T6下缘	导管贴壁	529	成功	完成治疗
7	男	76	25.6	T6下缘	导管移位	261	成功	完成治疗
8	男	56	28.1	T6下缘	导管移位	86	失败	切口不愈，取出TIVAP
9	男	57	30.8	T6下缘	导管移位	80	成功	完成治疗
10	女	71	23.2	T6下缘	导管阻塞	118	成功	完成治疗

患者	性别	年龄/岁	BMI/（kg/m²）	导管头端位置	并发症类型	随访时间/d	结局	远期结局
1	男	63	25.9	T6下缘	港体外露	763	失败	囊袋再次破裂，取出TIVAP
2	男	73	26.1	T7上缘	港体外露	337	成功	完成治疗
3	女	57	25.7	T6下缘	港体外露	281	成功	完成治疗
4	男	74	18.6	T6下缘	港体外露	557	成功	完成治疗
5	女	65	20.4	T6下缘	导管贴壁	181	成功	完成治疗
6	男	64	25.0	T6下缘	导管贴壁	529	成功	完成治疗
7	男	76	25.6	T6下缘	导管移位	261	成功	完成治疗
8	男	56	28.1	T6下缘	导管移位	86	失败	切口不愈，取出TIVAP
9	男	57	30.8	T6下缘	导管移位	80	成功	完成治疗
10	女	71	23.2	T6下缘	导管阻塞	118	成功	完成治疗

完全植入式静脉输液港非计划性取出后再植的可行性分析

Feasibility analysis of reimplantation after unplanned removal of totally implantable venous access ports

引用本文

RichHTML

PDF (PC)

可视化

摘要/Abstract

使用本文

图/表 2

参考文献 20

相关文章 0

编辑推荐

Metrics

本文评价