天津医药

• 临床论丛 • 上一篇    下一篇

呼吸道合胞病毒毛细支气管炎与血小板增多症的临床研究

李姣1,邹映雪2,马翠安3,翟嘉1   

  1. 1. 天津市儿童医院
    2. 天津儿童医院
    3. 天津市儿童医院呼吸内科
  • 收稿日期:2011-03-15 修回日期:2011-08-15 出版日期:2011-10-15 发布日期:2011-10-15
  • 通讯作者: 李姣

  • Received:2011-03-15 Revised:2011-08-15 Published:2011-10-15 Online:2011-10-15

PDF (PC)

2209

摘要： 摘要 目的：探讨呼吸道合胞病毒下呼吸道感染对婴幼儿血小板增多的潜在影响作用。方法：采用回顾性病例分析方法对490例确诊为毛细支气管炎的住院婴幼儿（年龄2~24月）的临床数据进行分析，并对比分析呼吸道合胞病毒阳性与呼吸道合胞病毒阴性患者血小板增多发生的比率。结果：呼吸道合胞病毒阳性组患者血小板增多的发生率明显高于阴性组（40.0% vs 24.5%，P＜0.05），但是2组血小板计数的平均值差异无统计学意义（49.5±12.5）vs（48.3±13.2）×109/L（p>0.05）。结果：婴幼儿罹患呼吸道合胞病毒毛细支气管炎者，易合并血小板增多症，其发生机制可能与呼吸道合胞病毒感染所致机体免疫失衡相关，临床应予以重视。

关键词: 呼吸道合胞病毒, 毛细支气管炎, 血小板增多症, 婴幼儿

Abstract: Respiratory Syncytial Virus Bronchiolitis is Associated with Thrombocytosis in Hospitalized Infants Lijiao,Zou yingxue,Ren lixin.Tianjin Children's Hospital.Tianjin,China,300074. Abstract Objectives: To assess the rate of thrombocytosis in hospitalized infants with bronchiolitis and to investigate its potential role as an early marker of respiratory syncytial virus infection. Methods: Clinical data on 490 infants aged 2~24 months who were hospitalized for bronchiolitis were collected prospectively and compared between RSV-positive and RSV-negative infants. Results: The rate of thrombocytosis was significantly higher in RSV-positive than RSV-negative infants (40.0% vs 24.5%, P＜0.05). There was no significant difference in mean platelet count between the two groups. Conclusions: RSV-positive bronchiolitis in hospitalized young infants is associated with thrombocytosis.

Key words: Respiratory Syncytial Virus, Bronchiolitis, Thrombocytosis, Infants