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牙周病与2型糖尿病及慢性血管并发症的关系

付秀立1,赵湜2,毛红2,李竞3   

  1. 1. 华中科技大学同济医学院附属武汉市中心医院
    2. 武汉市中心医院
    3. 武汉大学人民医院
  • 收稿日期:2010-06-29 修回日期:2010-10-05 出版日期:2011-03-15 发布日期:2011-03-15
  • 通讯作者: 付秀立

The relationship between Periodontal disease and chronic vasculopathy complications in Type 2 diabetes

  • Received:2010-06-29 Revised:2010-10-05 Published:2011-03-15 Online:2011-03-15

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摘要： 探讨2型糖尿病患者牙周病与慢性血管并发症的关系。方法 对166例2型糖尿病患者牙周情况与慢性血管并发症进行回顾性调查，并行相关影响因素的多元回归分析。结果 （1）糖尿病各亚组龈炎指数（GI）、牙周袋深度（PD）、临床附着丧失（CAL）明显高于正常对照组，糖尿病合并血管并发症高于无血管并发症组，差异具有统计学意义。（2）GI、PD、CAL与糖尿病病程、HbA1c成正相关。（3）Logistic回归分析显示GI、PD、CAL是影响糖尿病血管并发症的重要危险因素。结论 牙周病与糖尿病、血糖控制情况及慢性血管并发症密切相关。

关键词: 2型糖尿病, 牙周病, 血管并发症

Abstract: Objective To explore the relationship between periodontal disease and chronic vasculopathy complications in Type 2 diabetes. Methods retrospective study was untaken in 166 diabetic patients on periodontal examinations and chronic vasculopathy complications. Logistic analysis was conducted between diabetic cases with chronic vasculopathy complications for risk factors. Result (1) periodontal pocket depth(PD) ，gingivitis index (GI) and clinical attachment loss(CAL) were significantly increased in each groups with diabetes. The levels of PD , GI and CAL were higher in each diabetic complication group than in diabetic group without complications. (2)Durations of diabetes and HbA1c were positively correlated with PD ,GI and CAL. (3)The Logistic analysis showed that PD , GI and CAL were significantly related to diabetic groups with chronic vasculopathy complications. Conclusions There may be a correlation between Periodontal disease and chronic vasculopathy complications in Type 2 diabetes.

Key words: Diabetes mellitus type 2, Periodontal disease, Choronic complications