关键词: 肝硬化, 肝硬化性心肌病, B型利钠肽, 一氧化氮, 心脏功能, 彩色多普勒超声心脏检查, 红景天

Abstract: 【Abstract】　Objective　To explore the effects of Rhodiola Rosae in treatment of patients with cirrhotic cardiomyopathy (CCM). Methods　A total of 40 patients with CCM was randomly divided into group A(n=20) and B(n=20)，treated with routine method (group A) and Rhodiola Rosae capsule added routine method (group B)，respectively. Another 20 normal individuals were used as normal controls. The levels of serum NO were measured by the method of nitric acid reductase. The levels of plasma NT-proBNP were measured by the method of electrogenerated chemiluminescence. LVEF and the ratio of E/A were measured by color Doppler. Results LVEF and the ratio of E/A were significantly lower while the levels of serum NO and plasma NT-proBNP were significantly higher in group A and group B on admission as compared with group C(P<0.05). The levels of serum NO were significantly lower in group B on the 10d after treatment as compared with group B on admission(P<0.05). LVEF and the ratio of E/A were significantly higher while the levels of serum NO and plasma NT-proBNP were significantly lower in group B on the 30d after treatment as compared with group B on admission and group A on the 30d after treatment，and in group B on the 90d after treatment as compared with group B on admission and group A on the 90d after treatment，and also in group B on the 90d after treatmentas compared with group B on the 30d after treatment (P<0.05). Conclusions It is clear that Rhodiola Rosae can play a therapeutic role in CCM.

Key words: Liver cirrhosis, Cirrhotic cardiomyopathy, B-type natriuretic peptide, Nitric oxide, Cardiac function, Colour Doppler Ultrasound check, Rhodiola Rosae