天津医药

• 短篇论著 • 上一篇    下一篇

膝下动脉缺血治疗的临床研究

张华英   

  1. 天津市武清中医医院
  • 收稿日期:2010-10-22 修回日期:2011-03-30 出版日期:2011-09-15 发布日期:2011-09-15
  • 通讯作者: 张华英

The study on therapy for inferior genicular arterial occlusive disease

  • Received:2010-10-22 Revised:2011-03-30 Published:2011-09-15 Online:2011-09-15

PDF (PC)

2254

摘要： 目的：评价膝下动脉缺血性疾病的临床治疗选择。方法 将71例（101肢）膝下动脉缺血患者分为PTA治疗组（I组）和单纯药物治疗组（II组），分别按照年龄、病程、症状、跛行距离、踝/肱指数（ABI）、临床疗效、动脉通畅率等进行统计学分析。结果 I、II两组患者治疗14天后ABI平均增加值分别为0.52±0.04、0.04±0.01，两组相比差异有统计学意义（P＜0.05）。I组术后1年、2年一期通畅率分别为88.5%及65.2%，二期通畅率分别为96.2%及83.3%，救肢率为100%。结论 PTA作为膝下动脉缺血的治疗方法是可行、安全、有效的，推荐PTA作为首选治疗方法，其长期通畅性有待进一步观察。

关键词: 膝下动脉, 重度肢体缺血, 经皮腔内血管成形术

Abstract: objective To evaluate the therapy for inferior genicular arterial occlusive disease. Methods 71（101 limbs）patients with infrapopliteal artery ischemia were divided into two groups according to their therapy. Group I were treated with PTA；group II were only drug treatment. Their clinical features, ABI, clinical results, cumulative patency were collected and analyzed statistically. Results In this sudy, the average increased ABI is 0.52±0.04 in group I, 0.04±0.01 in group II at 14-day after-therapy. The degrees of increase had significant difference between two groups (P＜0.05). In group I, The arterial cumulative patency rate was 88.5% at 1-year, 65.2% at 2-year postoperatively, respectively. The secondary arterial patency rate was 96.2% at 1-year, 83.3% at 2-years postoperatively, respectively. The limb salvage rate was 100%. Conclusion PTA is a feasible, safe, and effective procedure, and it should be recommended as the first choice for patients with critical infrapopliteal limb ischemia. But the long term patency needs to be observed in the future.

Key words: Inferior genicular artery, Critical limb ischemia, Percutaneous transluminal angioplasty