• 临床论丛 • 上一篇    

脐尿管癌六例诊治分析

周煦东1,蔡启亮1,方平2,孙峰1,李伟1   

  1. 1. 天津医科大学第二医院
    2. 天津医科大学第二医院泌尿外科
  • 收稿日期:2012-05-22 修回日期:2012-08-22 出版日期:2013-03-15 发布日期:2013-03-15
  • 通讯作者: 周煦东

Diagnosis and treatment and prognosis of urachal carcinoma

  • Received:2012-05-22 Revised:2012-08-22 Published:2013-03-15 Online:2013-03-15

摘要:

【摘要】 <正>脐尿管癌是一种来源于脐尿管上皮的罕见恶性肿瘤,由于其初始症状的非特异性及发生部位的隐匿性,早期诊断较困难,预后较差。我院2007年8月—2011年5月共收治脐尿管癌患者6例,现将诊治情况报告如下。1临床资料1.1一般资料6例患者中男5例,女1例,年龄26~61岁,平均41岁。主要症状为间歇性无痛肉眼血尿,全程血尿2例, 

关键词: 脐尿管癌, 诊断, 治疗, 化疗, 预后

Abstract: [Abstract] Objective:To probe into the diagnosis,trestment and prognsis factors of urachal carcinoma. Methods:The clinical data,diagnosis,therapeutic regimen and the results of the prognosis of 6 cases of urachal carcinoma treated from 2007 to 2011 were review and analyzed.Results: Of 6 cases, 5 cases were treated by extensive partial cystectomy;1 case received radical cystectomy and modified cutaneous ureterostomy.Follow up 6~52 months,with an average of 24 moths. 2 cases died after 6, 23 months as distant metastasis,and the other 4 cases were tumorfree survival. Conclusion:Urachal carcinoma is a rare and highly malignant with poor prognosis. Surgical excision being the primary trestment.It is unclear whether radiation or chemotherapy are of any benefit to patients with urachal carcinoma,but some tumors may respond to cisplatin and/or 5FU based chemotherapy. Although the prognosis of this disease was bad,the extensive partial bladder excision can cure the majority of urachal cancers whose stages are low grade.Tumor stage and margin status were the strongest predictors of survival.

Key words: Urachal carcinoma, Diagnosis, Treatment, Chemotherapy, Prognosis