关键词: 脐尿管癌, 诊断, 治疗, 化疗, 预后

Abstract: [Abstract] Objective:To probe into the diagnosis,trestment and prognsis factors of urachal carcinoma. Methods:The clinical data,diagnosis,therapeutic regimen and the results of the prognosis of 6 cases of urachal carcinoma treated from 2007 to 2011 were review and analyzed.Results： Of 6 cases, 5 cases were treated by extensive partial cystectomy;1 case received radical cystectomy and modified cutaneous ureterostomy.Follow up 6~52 months,with an average of 24 moths. 2 cases died after 6, 23 months as distant metastasis,and the other 4 cases were tumorfree survival. Conclusion:Urachal carcinoma is a rare and highly malignant with poor prognosis. Surgical excision being the primary trestment.It is unclear whether radiation or chemotherapy are of any benefit to patients with urachal carcinoma,but some tumors may respond to cisplatin and/or 5FU based chemotherapy. Although the prognosis of this disease was bad,the extensive partial bladder excision can cure the majority of urachal cancers whose stages are low grade.Tumor stage and margin status were the strongest predictors of survival.

Key words: Urachal carcinoma, Diagnosis, Treatment, Chemotherapy, Prognosis