• 短篇论著 • 上一篇    下一篇

轻度认知障碍患者血管狭窄程度与脑电图功率谱改变的关系

姚扬   

  1. 天津市第一中心医院
  • 收稿日期:2013-01-29 修回日期:2013-09-17 出版日期:2014-01-15 发布日期:2014-01-15
  • 通讯作者: 姚扬

Studies on the electroencephalogram power spectrum changes in patients with mild cognitive impairment

Yang Yao   

  • Received:2013-01-29 Revised:2013-09-17 Published:2014-01-15 Online:2014-01-15
  • Contact: Yang Yao

摘要: 目的 研究轻度认知障碍 (MCI) 患者的颅内血管狭窄程度与脑电功率谱改变的关系。方法 将71例MCI患者根据其头核磁血管检查 (MRA) 分为3组, 无血管狭窄 (A) 组28例、 轻度血管狭窄 (B) 组23例及重度血管狭窄 (C) 组20例, 进行常规脑电图 (EEG) 记录, 比较分析3组的主频分布和频段相对功率值。结果 与A组(4.10±0.03) mV2/Hz比较, B组 (3.22±0.03) mV2/Hz、 C组 (2.41±0.02) mV2/Hz脑电图α2频段相对功率值下降。δ频段相对功率值升高, 3组依次为(1.31±0.01) mV2/Hz、(1.62±0.01) mV2/Hz和 (2.12±0.02) mV2/Hz。θ/α1值随着血管狭窄程度升高, 3组依次为0.72±0.06、 0.81±0.05和1.27±0.05。结论 MCI患者α2、 δ频段相对功率值及θ/α1值对患者血管狭窄程度可能具有提示意义。

关键词: 轻度认知障碍, 脑电图, 功率谱分析, 血管狭窄

Abstract: Objective:To explore the relations between the electroencephalogram power spectrum changes and cerebral artery stenosis (CAS)in patients with mild cognitive impairment (MCI). Methods: A total of 71 MCI patients were divided into three groups: non vascular damage group; moderate vascular damage group and severe vascular damage group according to head magnetic resonance angiography (MRA). EEGs were recorded at rest. Relative power was separately computed for ?, ?, ?1, ?2 and ?3 frequency bands. Results: In the spectral band power the severity of CAS was associated with increased ? power and decreased ?2 power. alpha3 power. The ?/?1 ratio increasing was consistent with the severity of CAS. All the differences were statistically significant. Conclusions: Together with ?/?1 ratio,?? and ?2 have great significance in indicating the severity of CAS in MCI patients.

Key words: mild cognitive impairment (MCI), EEG, power spectrum, cerebral artery stenosis