天津医药

天津医药 ›› 2017, Vol. 45 ›› Issue (8): 837-840.doi: 10.11958/20170754

• 专题 颅脑神经创伤 • 上一篇    下一篇

嗜酸乳杆菌联合电针刺激对重型颅脑创伤并发 胃肠功能障碍患者的影响

侯亚红， 张赛△   

  1. 武警后勤学院附属医院神经重症监护室 （邮编 300162）
  • 收稿日期:2017-06-29 修回日期:2017-07-24 出版日期:2017-08-15 发布日期:2017-08-15
  • 通讯作者: △通讯作者 E-mail: zhangsai718@vip.126.com E-mail:houyahongma@163.com
  • 作者简介:侯亚红 （1978）， 女， 博士， 主管护师， 讲师， 主要从事危重症患者的救护相关研究
  • 基金资助:
    武警后勤学院附属医院种子基金项目 （FYM201630）

The effectiveness of lactobacillus acidophilus combined with electroacupuncture on gastrointestinal function in patients with traumatic brain injury

HOU Ya-hong, ZHANG Sai△   

  1. Department of Neurological Intensive Critical Unit, the Affiliated Hospital of Logistics University of Chinese People’ s Armed Police Force, Tianjin 300162, China
  • Received:2017-06-29 Revised:2017-07-24 Published:2017-08-15 Online:2017-08-15
  • Contact: △Corresponding Author E-mail: zhangsai718@vip.126.com E-mail:houyahongma@163.com

PDF (PC)

3682

摘要： 目的 对比嗜酸乳杆菌联合电针刺激与单用嗜酸乳杆菌治疗对重型颅脑创伤 （TBI） 并发胃肠功能障碍患 者的治疗效果。方法 对武警后勤学院附属医院神经危重症医学科 2013 年 6 月—2016 年 12 月收治的 167 例颅脑 创伤并胃肠功能障碍的患者进行研究， 采用随机数字表法分为联合组 84 例， 嗜酸乳杆菌组 83 例。嗜酸乳杆菌组采 用常规治疗加嗜酸乳杆菌治疗； 联合组在常规治疗的基础上， 采用电针联合嗜酸乳杆菌治疗。评价 2 组在干预后的 胃肠道功能、 感染、 胃液 pH 值、 二胺氧化酶（DAO）和 D-乳酸水平。结果 联合组在干预后的胃内容物反流（χ2= 7.948）、 呕吐（χ2=7.514）、 腹泻（χ2=4.521）、 腹胀（χ2=5.968）、 肺部感染（χ2=4.521）和肠源性感染（χ2=4.531）的发生率均 低于嗜酸乳杆菌组（P＜0.05）。联合组在治疗后第 20 天胃液 pH 值（t=8.125）高于嗜酸乳杆菌组， 血浆 DAO（t= 6.383）和 D-乳酸水平（t=6.745）低于嗜酸乳杆菌组（P＜0.05）。结论 电针联合嗜酸乳杆菌治疗能够改善重型颅脑 创伤并发胃肠功能障碍， 促进胃酸分泌， 降低血浆 DAO 和 D-乳酸水平。

关键词: 颅脑损伤, 嗜酸乳杆菌, 电针, 胃肠功能障碍

Abstract: Objective To observe the effectiveness of lactobacillus acidophilus combined with electroacupuncture on gastrointestinal function in patients with traumatic brain injury. Methods A total of 167 patients with traumatic brain injury treated in our hospital from June 2013 to December 2016 were randomly divided into combining treatment group (n= 84) and lactobacillus acidophilus group (n=83). The lactobacillus acidophilus group was given routine treatment and lactobacillus acidophilus. The combining group was given the routine treatment, electroacupuncture treatment and lactobacillus acidophilus. Data of gastronintestinal function, infection, pH of gastric juice, serum two amine oxidase (DAO) and D-lacticacid level were compared between two groups. Results Compared with lactobacillus acidophilus group, the incidence rates of reflux (χ2=7.948), vomit (χ2=7.514), diarrhea (χ2=4.521), abdominal distension (χ2=5.968), pulmonary nfection (χ2=4.521) and enterogenic infection (χ2=4.531) were significantly decreased in the combining treatment group (P＜ 0.05). After 20- day treatment, pH value of gastric juice (t=8.125) was significantly increased, the serum DAO value (t= 6.383) and D-lacticacid level (t=6.745) were decreased, in combining treatment group than those of lactobacillus acidophilus group (P＜0.05). Conclusion Lactobacillus acidophilus combined with electroacupuncture can improve the gastrointestinal function, stimulate gastric acid secretion and decrease serum levels of DAO and D-lacticacid.

Key words: craniocerebral trauma, lactobacillus acidophilus, electroacupuncture, gastrointestinal dysfunction