天津医药 ›› 2018, Vol. 46 ›› Issue (8): 824-827.doi: 10.11958/20180509

• 专题 临床研究 • 上一篇    下一篇

以截瘫为临床表现的弥漫性大B细胞淋巴瘤合并甲状腺肿瘤一例

曹秋颖, 牛海玥, 齐薇薇, 王一浩, 江汇娟, 王化泉, 邵宗鸿   

  1. 天津医科大学总医院血液科 (邮编300052)
  • 收稿日期:2018-04-03 修回日期:2018-05-31 出版日期:2018-08-15 发布日期:2018-08-23
  • 通讯作者: 曹秋颖 E-mail:18202538044@163.com
  • 基金资助:
    重型再生障碍性贫血中免疫激活抗原的研究;CD4+CXCR5+细胞在骨髓增生异常综合征发病机制中作用的研究;CXCR5+CD8+T细胞在重型再生障碍性贫血免疫发病机制中作用的研究;MDSC介导的免疫抑制在骨髓增生异常综合征中作用的研究

A case report of diffuse large B-cell lymphoma combined with thyroid neoplasms with paraplegia as the clinical manifestation

CAO Qiu-ying, NIU Hai-yue, QI Wei-wei, WANG Yi-hao, JIANG Hui-juan, WANG Hua-quan, SHAO Zong-hong   

  1. Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China
  • Received:2018-04-03 Revised:2018-05-31 Published:2018-08-15 Online:2018-08-23
  • Contact: Qiu-Ying Cao E-mail:18202538044@163.com

摘要: 弥漫性大B细胞淋巴瘤 (DLBCL) 是非霍奇金淋巴瘤 (NHL) 中最常见的一个亚型, 发病年龄范围宽, 在临床特征、 侵袭部位、 组织形态学、 分子遗传学、 免疫表型等方面均表现出明显的异质性。此外, 随着恶性肿瘤诊治水平的提高, 同一患者存在多原发性恶性肿瘤 (MPMT) 的报道呈上升趋势。本文报告我科收治的以截瘫为临床表现的 DLBCL合并甲状腺肿瘤1例。

关键词: 截瘫, 淋巴瘤, 大B细胞, 弥漫性, 原发性骨淋巴瘤, 多原发性恶性肿瘤

Abstract:  Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-hodgkin’ s lymphoma (NHL), which has a wide range in age of onset, and has obvious heterogeneity in clinical features, invasive areas, histomorphology, molecular genetics and immune phenotype. In addition, with the improvement of the diagnosis and treatment of malignant tumor, the report of multiple primary malignant tumors (MPMT) in the same patient is on the rise. This paper reports a case of DLBCL combined with thyroid neoplasms with paraplegia as the clinical manifestation.

Key words:  paraplegia, lymphoma, large B-cell, diffuse, primary lymphoma of bone, multiple primary malignant tumors