光学相干断层扫描血管成像技术在慢性肾脏病临床评估中的应用进展

doi:10.11958/20231571

天津医药 ›› 2024, Vol. 52 ›› Issue (8): 882-887.doi: 10.11958/20231571

光学相干断层扫描血管成像技术在慢性肾脏病临床评估中的应用进展

马良¹(), 胡立影², 石羽², 龙刚¹^,^△()

1 天津市人民医院肾脏病科（邮编300121）
2 天津医科大学眼科医院临床研究中心

收稿日期:2023-10-13 修回日期:2023-12-25 出版日期:2024-08-15 发布日期:2024-08-16
通讯作者: △E-mail：longgang@hotmail.com
作者简介:马良（1984），男，主治医师，主要从事糖尿病肾病及慢性肾脏病机制方面研究。E-mail：rmyymaliang@163.com
基金资助:
天津市教委科研计划项目(2022KJ258)

Application of optical coherence tomography angiography in clinical evaluation of chronic kidney disease

MA Liang¹(), HU Liying², SHI Yu², LONG Gang¹^,^△()

1 Department of Nephrology, Tianjin Union Medical Center, Tianjin 300121, China
2 Clinical Research Center, Tianjin Medical University Eye Hospital

Received:2023-10-13 Revised:2023-12-25 Published:2024-08-15 Online:2024-08-16
Contact: △E-mail：longgang@hotmail.com

马良, 胡立影, 石羽, 龙刚. 光学相干断层扫描血管成像技术在慢性肾脏病临床评估中的应用进展[J]. 天津医药, 2024, 52(8): 882-887.

MA Liang, HU Liying, SHI Yu, LONG Gang. Application of optical coherence tomography angiography in clinical evaluation of chronic kidney disease[J]. Tianjin Medical Journal, 2024, 52(8): 882-887.

摘要/Abstract

摘要：

慢性肾脏病（CKD）是常见的慢性疾病。视网膜和肾脏具有同源性。糖尿病视网膜病变、视网膜神经血管损伤均揭示了视网膜和肾脏存在共同的病理生理特征。光学相干断层扫描血管成像技术（OCTA）可用接近组织学的分辨率检测脉络膜视网膜微循环。由于微血管结构和功能的改变可促进高血压、糖尿病、CKD及相关心血管疾病（CVD）的发展。OCTA对CKD患者眼底神经微血管的检查有助于识别高危人群，评估CKD病情的进展，为CVD风险预测提供了新的视角；其与深度学习的结合，将会进一步拓展该方面研究。

关键词: 肾功能不全, 慢性, 体层摄影术, 光学相干, 视网膜血管, 糖尿病视网膜病变, 心血管疾病

Abstract:

Chronic kidney disease (CKD) is a common chronic disease. There is homology between retina and kidneys. Diabetic retinopathy and retinal neurovascular injury both reveal common pathophysiological features of ocular retina and kidney. Optical coherence tomography angiography (OCTA) detects chorioretinal microcirculation with near-histological resolution. Changes in microvascular structure and function can promote the development of hypertension, diabetes, CKD and related cardiovascular disease (CVD). The examination of fundus nerve microvessels by OCTA in patients with CKD is helpful to the identification of high-risk groups, and provides a new perspective for the assessment of disease progression and CVD risk prediction of patients with CKD. The combination of the deep learning will further expand this aspect of research and become the forefront of future development.

Key words: renal insufficiency, chronic, tomography, optical coherence, retinal vessels, diabetic retinopathy, cardiovascular diseases

中图分类号:

R770.4，R774

参考文献 52

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光学相干断层扫描血管成像技术在慢性肾脏病临床评估中的应用进展

Application of optical coherence tomography angiography in clinical evaluation of chronic kidney disease

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