• 临床论丛 • 上一篇    下一篇

肺良性转移性平滑肌瘤(附一例报告及文献复习)

孙大强   

  1. 天津市胸科医院胸外科,天津医科大学胸科临床学院
  • 收稿日期:2010-03-08 修回日期:2010-06-13 出版日期:2010-11-15 发布日期:2010-11-15
  • 通讯作者: 孙大强

Pulmonary benign metastasizing leiomyoma:a case report and review of the literature

  • Received:2010-03-08 Revised:2010-06-13 Published:2010-11-15 Online:2010-11-15

摘要: [摘要] 目的 提高对肺良性转移性平滑肌瘤的认识。 方法 结合1例肺良性转移性平滑肌瘤患者的临床资料和文献复习,对本病的病因、病理、临床表现、诊断和治疗等进行讨论。 结果 本病的病因目前仍有争议;病理表现主要为肿瘤病灶内平滑肌细胞结缔组织纤维交错排列,有时可发现腺体样结构,肿瘤细胞可以发生退行性改变;患者常无临床症状;影像学检查主要表现为两肺多发性结节影;确定诊断需要依靠病理学检查;治疗包括手术和激素调控两方面。 结论 肺良性转移性平滑肌瘤是一种非常罕见的疾病,易误诊,在双肺多发结节的诊断中应想到此病的可能。

关键词: 肺肿瘤, 良性, 转移性, 平滑肌瘤

Abstract: Pulmonary benign metastasizing leiomyoma:a case report and review of the literature  Sun Daqiang , Zhang Xun , Han Qingliang ,Xu Feng Corresponding author:Zhang Xun , E-mail:zhangxun69@163.com Department of Thoracic Surgery , Chest clinical institute of Tianjin Medical University(Tianjin Chest Hospital) , Tianjin 300051 , China Abstract Objective  To highlight the characteristics of pulmonary benign metastasizing leiomyoma (PBML). Methods With a case report and review of the related literatures , the pathogenesis , clinical manifestations ,diagnosis , management and prognosis of pulmonary benign metastasizing leiomyoma were described. Results The pathogenesis of PBML remains controversial . The pathologic feature is that the tumor appears as interlacing bundles of smooth muscle cells and connective tissue , containing glandular appearing structures .Leiomyomas may undergo degenerative changes. There is few symptoms in most patients with PBML . Chest radiograph or computed tomography usually reveals multiple bilateral pulmonary nodules . PBML can be definitely diagnosed by histopathology and treated with pulmonary surgery and hormonal manipulation . The clinical course of PBML in most patients is benign. Conclusions  Being rare and often misdiagnosed , PBML should be considered in patients showing multiple bilateral pulmonary nodules.

Key words: Lungneoplasms, Benign, metastasizing, Leiomyoma