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高原肺水肿继发急性呼吸窘迫综合征氧动力学变化特点及治疗

李保存1,马四清2,李洪喜3   

  1. 1. 青海卫生职业技术学院
    2.
    3. 青海省格尔木市人民医院
  • 收稿日期:2009-11-25 修回日期:2010-03-10 出版日期:2010-10-15 发布日期:2010-10-15
  • 通讯作者: 李保存

The treatment and monitor of oxygen dynamic of high altitude pulmonary edema patients with secondary adult respiratoyy distress syndeome

  • Received:2009-11-25 Revised:2010-03-10 Published:2010-10-15 Online:2010-10-15

摘要: 目的 探讨高原肺水肿继发急性呼吸窘迫综合征氧动力学变化特点及治疗。方法 采用右心漂浮导管及热稀释法,对8例高原肺水肿继发急性呼吸窘迫综合征患者进行了氧动力学监测,并提出治疗方法。结果 监测开始时,右房压(RAP)、肺动脉平均压(mPAP)、肺循环阻力指数(PVRI)、肺内分流(Qs/Qt)明显增加,心输出指数(CI)、氧输送(DO2)、氧耗量(VO2 )、氧摄取(O2ext)、氧和指数(PaO2/FiO2)明显减低;监测结束时,RAPP、mPAP、PVRI、Qs/Qt明显减低(P<0.05),而CI、DO2、VO2、O2ext、PaO2/FiO2明显增加(P<0.05),8例患者全部存活。结论 高原肺水肿继发急性呼吸窘迫综合征时氧动力学已发生明显紊乱,病情危重,治疗的关键是早期机械通气,提高养输送,改善组织氧合。

关键词: 高原肺水肿, 急性呼吸窘迫综合征, 氧动力学, 监测, 治疗

Abstract: Objective To investigate the changed characteristics of oxygen dynamic and treatment Strategies of high altitude pulmonary edema(HAPE) patients with secondary acute respiratory distress Syndrome(ARDS).Methods 8 HAPE with secondary ARDS patients data of oxygen dynamic were Monitiored with Swan-Ganz catheter;treatment methods were put forward. Results At the beginning Of monitor, the patients data of RAP、mPAP、PVRI、Qs/Qt increase significantly,cardiac output index(CI)、oxygen delivery(DO2)、oxygen consumption(V O2)、oxygen extraction rate(O2ext)、 PaO2/FiO2 decrease significantly;At the end of monitor, the patients data of RAP、mPAP、PVRI、Qs/Qt decrease significantly(P<0.05),CI、DO2、VO2、O2ext、PaO2/FiO2increase significantly(P<0.05),8 patients all survivaled.Conclutions HAPE with secondary ARDS patients data of hemodynamic、oxygen dynamic has disordered greatly.Therefore,early support of ventilation to improve hypoxia,enhance oxygen delivery is the most important treatment mesure..

Key words: Acute high altitude edema, Acute respiratory distress syndrome, Oxygen dynamic, Monitior, Treatment