天津医药

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种植体骨界面对非血管化下颌骨植骨后即刻种植的骨结合实验研究

崔江涛1,彭诚2,李小东3,董华4   

  1. 1. 天津医科大学第二医院口腔科
    2. 天津市医科大学第二医院
    3. 天津医科大学第二医院
    4. 天津医大二院核医学科
  • 收稿日期:2011-09-19 修回日期:2011-10-08 出版日期:2011-12-15 发布日期:2011-12-15
  • 通讯作者: 崔江涛

The evaluation of the bone contact of immediate implants after the mandibular non-vascularized bone graft by the examination of the SPECT/CT fusion imaging and histology

  • Received:2011-09-19 Revised:2011-10-08 Published:2011-12-15 Online:2011-12-15

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摘要： 摘要 目的：评价种植体骨界面对非血管化下颌骨植骨后即刻种植的骨结合效果。方法：选择12~15个月的健康本地杂种犬6只，全身麻醉后将其一侧下颌骨作为实验侧切开后矩形截骨，移植游离髂骨置于下颌骨缺损区, 在植骨区植入种植体3枚。对照侧同样位置上植入3枚种植体。所有动物于12周时接受单光子发射计算机断层仪/计算机断层扫描（SPECT/CT）融合显像检查后处死，并采用带种植体硬组织磨片对18枚种植体骨界面组织学和骨结合率进行分析。结果：12周时所有种植体骨界面组织均愈合良好；两侧种植体骨结合界面感兴趣区（ROI）放射性计数、CT值、骨结合率和周围骨面积差别均无统计学意义（P＞0.05）；结论：非血管化下颌骨植骨后即刻种植的骨结合效果较好，SPECT/CT融合显像和带种植体硬组织磨片技术在分析种植成功率方面有重要价值。

关键词: 体层摄影术, 发射型计算机, 单光子, 体层摄影术, 发射型计算机, 骨移植, 牙种植体

Abstract: [Abstract] Objective To evaluate the bone contact of immediate implant after the mandibular non-vascularized bone graft by the examination of the SPECT/CT fusion imaging and histology . Method Six local healthy crossbred dogs were choosed as the experimental animals. The opration of bone rectangular cutting was performed to one side of the mandibular of the experimental animals under general anesthesia. The non-vascularized iliac bone was grafed to repair the jaw defect. 3 dental implants were planted the graft bone and the control side at the same time. All the experimental animal were killed at 12 weeks after the exmanation of the SPECT/CT fusion imaging, and ground section of bone with dental implant was performed to access the histology in the implant-bone interface, bone-implant contact ratio and mineralized bone area of 18 implnts. Result All dental imlant-bone interface healed well. There was no statistical significance in the difference in the radioactivecounting of the region of interest, the CT value, the bone-implant contact ratio and mineralized bone area of immediate dental implant in the mandibular which was the non-vascularized bone graft or the normal mandibular. Conclusion Immediate implant after the mandibular non-vascularized bone graft is high feasible. The ground section of bone with dental implant and the SPECT/CT fusion imaging showed important value in the analysis of the successful ratio of the imlant.