天津医药

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老年冠心病患者肌酐清除率和总胆红素水平临床分析

耿婕1,陈树涛1,王林2   

  1. 1. 天津市胸科医院
    2. 天津医科大学第二医院
  • 收稿日期:2010-09-07 修回日期:2010-11-25 出版日期:2011-04-15 发布日期:2011-04-15
  • 通讯作者: 王林

Clinical Analysis of Creatinine Clearance and Total Bilirubin Levels in Aged Patients with Coronary Heart Disease

  • Received:2010-09-07 Revised:2010-11-25 Published:2011-04-15 Online:2011-04-15

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摘要： 目的：探讨肌酐清除率和总胆红素水平对于老年冠心病人的临床意义。方法：选择784例65岁以上老年患者，根据冠脉造影结果进行分组，比较肌酐清除率（Ccr）和总胆红素（TBIL）水平。结果：随冠脉病变的逐渐加重Ccr水平明显下降，TBIL水平明显升高（P<0.05）。多元Logistic逐步回归分析表明Ccr和TBIL是冠心病的独立危险因素。结论：Ccr和TBIL对于老年冠心病的发生及严重程度具有一定的临床预测价值，治疗老年冠心病时需关注患者的肝肾功能。

关键词: 冠状动脉疾病, 肌酐清除率, 总胆红素, 老年

Abstract: Abstract Objective: To explore the clinical significance of creatinine clearance（Ccr）and total bilirubin（TBIL）Levels in aged patients with coronary heart disease. Methods: According to coronary artery angiography (CAG), 784 subjects aged more than 65 years were divided into several groups. The creatinine clearance and total bilirubin Levels were compared. Results: With the increased number of involved branches, the level of Ccr was gradually decreased, the level of TBIL was gradually increased (P<0.05). Multi-Logistic regression analysis showed that Ccr and TBIL were independent risk factors of CHD. Conclusion: Ccr and TBIL may have clinical forecast value for CHD. It was important to improve renal and liver functions in intervention and prevention of aged patients with coronary heart disease.

Key words: coronary disease, creatinine clearance, total bilirubin, aged