天津医药

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应变率成像评价高血压患者左房功能的价值

刘雯   

  1. 天津医科大学，天津医科大学总医院，天津市公安医院
  • 收稿日期:2010-09-02 修回日期:2010-12-29 出版日期:2011-04-15 发布日期:2011-04-15
  • 通讯作者: 刘雯

Assessment of Left Atrial Function by Strian Rate Imaging in Patients with Hypertension

  • Received:2010-09-02 Revised:2010-12-29 Published:2011-04-15 Online:2011-04-15

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摘要： 摘要 目的：探讨应变率成像（SRI）评价高血压病患者左房功能的临床价值。方法：原发性高血压病患者89例，分为左室正常构型组（LVN）40例和左室重构组（LVR）49例；正常人41例为对照组。于心尖四腔切面，应用SRI获取左房侧壁中段应变率曲线，分别测量左室收缩期、舒张早期、舒张晚期左房峰值应变率(SRs、SRe、SRa)；应用组织多普勒成像（TDI）获得二尖瓣环附着处左室舒张早期及舒张晚期峰值速率（Ea、Aa），计算Ea/Aa。应用脉冲多普勒（PW）测量二尖瓣E峰及A峰流速（E、A），计算E/A；应用二维超声测量左房前后径（LAD）。 结果：与对照组比较，高血压各组SRe及SRs均减低，LVN组SRa增高（p＜0.01）；高血压各组Ea/Aa均减低，LVR组 E/A减低（p＜0.01）；高血压各组LAD均增高，且LVR组大于LVN组（p＜0.01）。 结论： SRa、SRe、SRs能够评价高血压病患者左房收缩及舒张功能。

关键词: 应变率成像, 高血压, 左房功能

Abstract: Abstract Objective: To evaluate the clinical value of left atrial function in primary hypertensive patients by Strian Rate Imaging(SRI). Methods:89 patients with primary hypertensions were divided into groups of normal geometry (LVN,n= 40) and remodeling geometry (LVR, n= 49).41 healthy participants were also included.At four-chamber view,the strain rate curves was gained in the middle segments of each left atrial lateral wall by SRI.Strain rate parameters SRs were measured during left ventrial systolic phase,SRe and SRa were measured during left ventrial diastolic early phase and later phase;Peak velocity during left ventrial diastolic early phase and later phase (Ea and Aa) at the left ventricle lateral wall of annulus mitral valve were measured on Tissure Doppler imaging(TDI),then Ea/Aa were calculate. E Peak and A Peak velocity (E and A) of bicuspid were measured on pulsed wave Doppler(PW),then E/A were calculate.Left atrial AP diamind(LAD) were measured on 2D. Results: Compared with the control group, the SRs and SRe were reduced in two hypertensive Group,meanwhile the SRa was higher in LVN group（p＜0.01）;Ea/Aa were reduced in two hypertensive group,E/A were reduced in LVR group（p＜0.01）, LAD was higher in two hypertensive group and LAD in LVR was higher than that in LVN（p＜0.01）.Conclusions: The SRa、SRe and SRs can assess left atrial systolic and diastolic function.

Key words: strain rate imaging, hypertension, left atrial function