天津医药

天津医药 ›› 2015, Vol. 43 ›› Issue (7): 765-768.doi: 10.11958/j.issn.0253-9896.2015.07.018

• 临床研究 • 上一篇    下一篇

体质指数、血脂水平与前列腺穿刺阳性间的关系

张浩宇，吕广霖，袁和兴，魏雪栋，胡林昆，张学锋，侯建全   

  1. 苏州大学附属第一医院泌尿外科（邮编 215000）

  • 收稿日期:2014-11-07 修回日期:2015-02-06 出版日期:2015-07-15 发布日期:2015-07-15
  • 通讯作者: 侯建全 E-mail:harryzhanghy@126.com

Relationship of body mass index and blood lipid level with cancer detection on prostate biopsy

ZHANG Haoyu, LYU Guanglin, YUAN Hexing, WEI Xuedong, HU Linkun, ZHANG Xuefeng, HOU Jianquan   

  1. Department of Urology, First Affiliated Hospital of Soochow University, Suzhou 215000, China

  • Received:2014-11-07 Revised:2015-02-06 Published:2015-07-15 Online:2015-07-15
  • Contact: HOU Jianquan E-mail:harryzhanghy@126.com

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摘要： 摘要：目的 探讨体质指数(BMI)、血脂水平与前列腺穿刺阳性之间的关系。方法 回顾分析2013年2月—2014年8月间在我院行前列腺穿刺活检患者214例，根据穿刺病理结果分为前列腺癌组和非癌组，比较2组间年龄、前列腺特异性抗原（PSA）、前列腺体积（PV）、血脂水平、体质指数（BMI）等指标，并分析前列腺穿刺阳性的危险因素。结果 前列腺癌组年龄、PSA、BMI高于非癌组，而PV、高密度脂蛋白胆固醇（HDL-c）则低于非癌组（均P<0.05）。Logistic回归分析提示年龄大，PSA、BMI升高是前列腺穿刺阳性的危险因素，而PV、HDL-c升高则为保护因素（均P<0.05）。结论 综合评估患者BMI及血脂水平可为前列腺癌的早期筛查及前列腺穿刺方案的制定提供重要信息，对高危人群的早预防、早诊断、早治疗提供重要依据。

关键词: 前列腺肿瘤, 穿刺术, 人体质量指数, 胆固醇, HDL, 前列腺特异抗原, 前列腺体积

Abstract: Abstract: Objective To investigate the relationship between body mass index (BMI), blood lipid level and cancer dectection on prostate biopsy. Methods A total of 214 patients undergoing a prostate biopsy during 2013.2—2014.8 were reviewed retrospectively. They were divided into prostate cancer and non-cancer groups by biopsy results. The differences of age, prostate-specific antigen (PSA) level, prostate volume (PV), blood lipid level and BMI between two gtoups were analyzed. Risk factors for cancer dectection on biopsy were also analyzed. Results Compared with non-cancer patients, prostate cancer patients were older, had higher PSA level and BMI, but smaller PV and lower HDL-c level (P<0.05). Logistic regression analysis showed that older, higher PSA level and BMI were risk factors for cancer dectection on biopsy, but larger PV and higher HDL-c level were protective factors (P<0.05). Conclusion Comprehensive assessment of patients’ BMI and blood lipid levels can provide important reference for prostate cancer screening at early time and establishment of prostate biopsy scheme, which also provide significant evidence for the prevention, diagnosis and treatment of prostate cancer at early stage for high risk population.

Key words: prostatic neoplasms, punctures, body mass index, cholesterol, HDL, prostate-specific antigen, prostate volume