天津医药

天津医药 ›› 2015, Vol. 43 ›› Issue (7): 807-810.doi: 10.11958/j.issn.0253-9896.2015.07.029

• 流行病学调查 • 上一篇    下一篇

脑卒中家族史人群的脑卒中危险因素筛查

董文涛，张振，靳张宁，高峰，张利通，李锋坦，王景华，杨新宇   

  1. 天津医科大学总医院神经外科
    2 天津市神经病学研究所

  • 收稿日期:2014-11-04 修回日期:2015-03-02 出版日期:2015-07-15 发布日期:2015-07-15
  • 通讯作者: 杨新宇 1△ E-mail:gaoxiaofeng0927@126.com

Screening for risk factors of stroke in people with family history of stroke

DONG Wentao, ZHANG Zhen, JIN Zhangning, GAO Feng, ZHANG Litong, LI Fengtan, WANG Jinghua, YANG Xinyu   

  1. 1 Tianjin Medical University General Hospital, Tianjin 
    2 Tianjin Neurological Institute

  • Received:2014-11-04 Revised:2015-03-02 Published:2015-07-15 Online:2015-07-15
  • Contact: YANG Xinyu1△ E-mail:gaoxiaofeng0927@126.com

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摘要： 目的 探讨天津蓟县农村地区有脑卒中家族史人群的脑血管影像学特点及其脑卒中的危险因素。方法 招募该地区有脑卒中家族史的志愿者进行头CT及脑血管CTA检查、体格检查和实验室检查。共检查281人，男性153人，女性128人。结果 男性吸烟率、饮酒率、受教育程度以及低HDL检出率高于女性，女性高TG检出率高于男性，差异均有统计学意义（P<0.05）。38人为脑卒中组，脑卒中组年龄、颈内动脉钙化率及颈内动脉迂曲率高于非脑卒中组，差异具有统计学意义（P<0.05）。多因素Logistic回归分析结果显示年龄、高血压、颈内动脉钙化及迂曲是该人群脑卒中发生的独立危险因素。结论 对于有脑卒中家族史的人群来说，年龄、高血压、颈内动脉钙化或者颈内动脉迂曲是发生脑卒中的危险因素。

关键词: 卒中, Logistic 模型, 危险因素, 高血压, 颈内动脉, 颈内动脉钙化, 颈内动脉迂曲, 家族史

Abstract: Objective To investigate the characteristics of cerebral vascular imaging and the risk factors of stroke in population with family history of stroke in rural areas of Ji County, Tianjin. Methods Area volunteers with family history of stroke were recruited in the study area to undergo computed tomography and computed tomography angiography of the brain as well as physical and laboratory examinations. A total of 281 subjects underwent examination,153 were men and 128 were women. Results The smoking rate, drinking rate, educational level, and low HDL-C level detection rate were higher among men than among women, whereas the high TG level detection rate was higher among female subjects than among male subjects; all of these differences were statistically significant (p < 0.05).38 subjects belong to the stroke group, The age, internal carotid artery calcification rate(ICAC), and internal carotid artery tortuosity(ICAT) rate were significantly higher in the stroke group than in the non-stroke group (p < 0.05) . The results of multivariate logistic regression analysis indicated that Age, SBP, ICAC, and ICAT were independent risk factors for stroke. Conclusion For population with family history of stroke, age, hypertension, ICAC and ICAT were risk factors of stroke.

Key words: stroke, logistic models, risk factors, hypertension, carotid artery, internal, internal carotid artery calcifica?tion, internal carotid artery tortuosity, family history