天津医药

天津医药 ›› 2015, Vol. 43 ›› Issue (2): 147-149.doi: 10.11958/j.issn.0253-9896.2015.02.009

• 实验研究 • 上一篇    下一篇

电针刺激对 Beagle 犬展神经损伤修复的研究

张毅1 ， 陈霞1 ,周凌云2 ， 王旭东3 ， 虞昊1   

  1. 1江苏省南通大学第二附属医院神经外科(邮编226001)； 2哈尔滨医科大学附属第一医院针灸科； 3南通大学第二附属医院中医科
  • 收稿日期:2014-08-28 修回日期:2014-10-14 出版日期:2015-02-15 发布日期:2015-02-27
  • 基金资助:
    黑龙江省自然科学基金项目 （ZD201211);南通市社会事业科技创新与示范计划项目 （HS2012031）

Effect of electroacupuncture on abducens nerve injury in Beagle dog

  • Received:2014-08-28 Revised:2014-10-14 Published:2015-02-15 Online:2015-02-27

PDF (PC)

3916

摘要： 摘要： 目的 建立展神经损伤电针刺激的动物模型， 研究电针刺激对展神经损伤修复的疗效。方法 24 只 Bea⁃ gle 犬随机均分为单纯损伤组(对照组)及损伤后电针刺激组(实验组)。行展神经脑池段压榨损伤， 展神经刺激电极及外直肌记录电极植入。于术后 1～12 周， 测量 2 组瞳孔中心至外眦内侧缘距离。结果 所有 Beagle 犬均能耐受手术， 颅内刺激电极和外直肌记录电极成功植入； 术后 1～2 周， 2 组 Beagle 犬瞳孔中心至外眦内侧缘距离比较差异无统计学意义， 术后 4～12 周， 实验组 Beagle 犬瞳孔中心至外眦内侧缘距离小于对照组(P＜0.01)。结论 成功建立应用于展神经损伤电针刺激的动物模型， 电针刺激可以明显促进损伤的展神经恢复。

关键词: 犬科, 电针, 展神经损伤, Beagle 犬

Abstract: Abstract:Objective To establish Beagle dogs’model of abducens nerves injury and to observe the clinical therapeu⁃ tic effect of electroacupuncture treatment. Methods Twenty-four Beagle dogs were randomly divided into simple crush group (control group) and crush with electrical stimulation group (experimental group). Cisternal segment of the abducens nerve was given a crush injury, then electrodes were implanted to stimulate the abducens nerve and lateral rectus muscle. Distance between the center of the pupil to medial margin of extraocular adjoin was measured from 1 to 12 weeks after opera⁃ tions. Results All procedures used in the study were well tolerated by Beagle dogs. Electrode implantation to stimulate the lateral rectus muscle and the abducens nerve behind of cavemous sinus was successful. There was no statistical significance of the distance between the two groups from 1 to 2 weeks after operations, and the distance was shorter in experimental group than that in control group from 4 to 12 weeks after operations (P < 0.01). Conclusion The animal models established to study electroacupuncture treatment of the injured abducens nerves was successful. Electroacupuncture can promote the re⁃ covery of the injured abducens nerves obviously.

Key words: canidae, electroacupuncture, abducens nerve injury, beagle dogs