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唐山市946例煤炭从业人员高尿酸血症患病情况分析

田炜1,郝志梅1,马宇杰2   

  1. 1. 河北联合大学
    2. 华北煤炭医学院附属开滦医院
  • 收稿日期:2011-11-29 修回日期:2012-04-10 出版日期:2012-10-15 发布日期:2012-10-15
  • 通讯作者: 田炜

Characteristics and risk factor of hyperuricemia among 946 coal industry employee in Tangshan city

  • Received:2011-11-29 Revised:2012-04-10 Published:2012-10-15 Online:2012-10-15
  • Contact: Wei TIAN

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摘要： 目的：了解唐山市煤炭行业从业人员高尿酸血症（HUA）的患病情况和相关危险因素。方法：选取唐山市煤炭行业从业人员共946人，询问一般情况、个人生活习惯、家族疾病史等，测定身高、体质量和血压。取空腹肘正中静脉血检测血尿酸、血糖、总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-C）和低密度脂蛋白胆固醇（LDL-C），并对检测结果进行分析。结果：HUA检出率10.7%，HUA组的体质指数、TG、TC、SBP、DBP高于非HUA组（P<0.05）。HUA组中男性、肥胖、吸烟、饮酒、高血压家族史、高血压、血脂异常者所占比例大于非HUA组（P<0.05），多因素分析显示性别、肥胖、血脂异常、高血压是HUA的独立危险因素。结论：煤炭行业从业人员HUA检出率较高，脂质代谢异常、高血压及不良生活习惯是其主要危险因素。

关键词: 高尿酸血症, 采煤, 危险因素, 体格检查

Abstract: Abstract Objective: To analyze the characteristics and risk factor of hyperuricemia (HUA) among coal industry employee. Methods: The survey population in this study is 946 coal industry employees in Tangshan city. Inquiring about the general situation, personal habits, family history of disease, and determination of height, body mass and blood pressure. We analysis indicators of blood uric acid, blood glucose testing, total cholesterol (TC), Triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C). Results: The detectable rate of HUA was 10.7%. There was a remarkable statistical difference of BMI, TG, TC, SBP, DBP in subjects without HUA and with HUA (P<0.05). There is highly rate of men, obesity, current smoking, current drinking, history of HP, HP, dyslipidemia in subjects with HUA (P<0.05). Multivariate analysis showed that sex, obesity, dyslipidemia, hypertension are risk factories of HUA. Conclusions: There was a highly detectable rate of HUA in coal industry employee. Abnormal lipid metabolism, HP and unhealthy lifestyle habits maybe its causative factor.

Key words: hyperuricemia, coal mining, risk factors, physical examination