天津医药

天津医药 ›› 2015, Vol. 43 ›› Issue (8): 909-911.doi: 10.11958/j.issn.0253-9896.2015.08.022

• 应用研究 • 上一篇    下一篇

2 型糖尿病患者下肢胫神经超声表现与密歇根筛查量表评分的相关性

王艳滨，韩云霞，党磊，刘晓玲   

  1. 1河北省唐山市工人医院超声诊断科(邮编063000)；2河北联合大学
  • 收稿日期:2015-01-21 修回日期:2015-02-16 出版日期:2015-08-15 发布日期:2015-08-15
  • 作者简介:王艳滨（1967），女，博士，主任医师，主要从事超声诊断学研究

Correlation between ultrasonic feature of tibial nerve with Michigan neuropathy screening instrument scoring system in type 2 diabetic mellitus

WANG Yanbin, HAN Yunxia, DANG Lei, LIU Xiaoling   

  1. 1 Department of Ultrasound, Tangshan Gongren Hospital, Tangshan 063000, China; 2 Hebei United University
  • Received:2015-01-21 Revised:2015-02-16 Published:2015-08-15 Online:2015-08-15

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摘要： 目的探讨糖尿病患者下肢胫神经形态学参数以及声像图特征与密歇根筛查量表（MNSI）评分之间的相关性，为糖尿病周围神经病变的早期诊断提供影像学信息。方法选取我院收治的95 例2 型糖尿病患者，以30 例健康志愿者作为对照（A 组）。根据MNSI 评分结果，将糖尿病患者分为B 组（32 例，0~2.4 分）、C 组（31 例，2.5~4.4 分）及D 组（32 例，≥4.5 分），高频超声检测4 组对象胫神经的形态学参数以及声像图特征；分析MNSI 评分与胫神经形态学参数的相关性。结果与A 组相比，B 组胫神经的横径无明显变化（P > 0.05），C、D 组胫神经的前后径、横径、截面积增大（均P < 0.05）。C、D 组胫神经声像图异常改变的发生率高于B 组（P < 0.05）。胫神经的前后径、横径、截面积与MNSI 评分呈正相关（rs 分别为0.656、0.657 和0.681，均P < 0.05）。结论MNSI 评分与胫神经超声形态学参数及声像图特征具有一定的相关性，且评分越高，胫神经超声表现异常的可能性越大。

关键词: 糖尿病, 2 型, 糖尿病周围神经病变, 超声检查, 多普勒, 彩色, 胫神经, 密歇根筛查量表

Abstract: Objective To examine the correlation between the ultrasonic feature of tibial nerve and the scores of Michi⁃ gan neuropathy screening instrument（MNSI）in type 2 diabetic mellitus (T2DM) and to provide information for early diagno⁃ sis of diabetic peripheral neuropathy（DPN）. Methods Based on scores of MNSI, 95 cases of T2DM patients were divided into three different groups: group B（0-2.4 scores）, C（2.5-4.4 scores）and D（≥4.5 scores）. Ultrasound parameters of group A (n=30) were compared with group B (n=32), group C (n=31) and group D (n=32). These parameters includes nerves′s an⁃ teroposterior dimension, transverse diameter, cross-sectional area and fasciculus echo, the "screen cloth" structure, epineuri⁃ um and the demarcation with neighbourhood structures. Correlation of MNSI with ultrasound performance of tibia nerve was also tested. Results Compared with group A, transverse diameter in group B did not show a obvious change, but anteropos⁃ teror dimension, transverse diameter, cross-sectional area in group C, group D all increase.（P < 0.05）. Compared with group B，ultrasound alteration were more frequent in group C and group D（P < 0.05）, but there was no statistical difference on that between group C and group D（P > 0.05）. There was a positive correlation between the nerves′s anteroposterior di⁃ mension, transverse diameter, cross-sectional area with MNSI, rs were 0.656、0.657 and 0.681 respectively (P < 0.05 in all three cases). Conclusion Certain correlation was observed between MNSI and tibial never ultrasonic feature in T2DM pa⁃ tients; the higher MNSI scores , the greater chance of presence of abnormal sonographic features of tibial nerve.

Key words: words, diabetes mellitus, type 2, diabetic peripheral neuropathy, ultrasonograpy, doppler, color, tibial nerve, michigan neuropathy screening instrument