天津医药

天津医药 ›› 2017, Vol. 45 ›› Issue (10): 1057-1060.doi: 10.11958/20170710

• 临床研究 • 上一篇    下一篇

阴式卵巢囊肿剥除术对卵巢储备功能影响及 临床疗效的对比分析

黄静 1，罗亚辉 2，王楠 3   

  1. 1 陕西省安康市宁陕县医院妇产科（邮编 711699）；2 陕西省安康市人民医院妇产科；3 解放军总医院妇产科
  • 收稿日期:2017-06-19 修回日期:2017-07-23 出版日期:2017-10-15 发布日期:2017-10-13
  • 通讯作者: 黄静 E-mail:jessica_huang2017@163.com
  • 作者简介:黄静（1979），女，主治医师，本科，主要从事妇科良性疾病微创手术治疗方面研究
  • 基金资助:
    高通量测序探寻子宫内膜异位症致病基因的研究

Analysis of the clinical effect of vaginal ovarian cystectomy on ovarian reserve

HUANG Jing1, LUO Ya-hui2, WANG Nan3   

  1. 1 Department of Obstetrics and Gynecology, Ningshan County Hospital, Shaanxi 711699, China; 2 Department of Obstetrics and Gynecology, Ankang City People’s Hospital; 3 Department of Obstetrics and Gynecology, General Hospital of PLA
  • Received:2017-06-19 Revised:2017-07-23 Published:2017-10-15 Online:2017-10-13
  • Contact: HUANG Jing E-mail:jessica_huang2017@163.com

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摘要： 目的 比较阴式卵巢囊肿剥除术和腹腔镜卵巢囊肿剥除术的临床疗效。方法 2013 年 6 月—2016 年 6 月在本院妇产科收治的卵巢囊肿病例中，根据微创手术方式（阴式手术和腹腔镜手术）分为观察组 55 例，对照组 49 例。2 组患者平均年龄、体质量指数（BMI）、腹部手术史、囊肿直径、囊肿类型以及单双侧构成差异均无统计学意义； 观察 2 组手术时间、术中出血量、住院费用和平均住院日以及手术前后卵巢储备功能情况。结果 观察组手术时间 ［（46.9±18.4）min vs. （62.3±26.5）min］、住院费用［（8 165.3±951.8）元 vs. （12 543.9±1 464.4）元］和平均住院日［（4.5±1.9） d vs. （6.8±2.3）d］少于对照组，差异均有统计学意义（P＜0.05）；2 组手术前雌二醇（E2）、卵泡刺激素/黄体生成素（FSH/ LH）、卵泡刺激素（FSH）和窦卵泡数差异无统计学意义；手术后观察组 FSH/LH（1.4±0.4 vs. 1.8±0.6）、FSH［（9.2±2.9） U/L vs. （13.6±4.3）U/L］低于对照组（P＜0.05）；观察组窦卵泡数多于对照组［（7.2±1.6）个 vs. （6.0±1.3）个，P＜0.05］。结 论 阴式卵巢囊肿剥除术对卵巢储备功能损伤小，适合育龄期女性患者，符合“价值医学”的要求。

关键词: 卵巢囊肿, 腹腔镜检查, 阴式手术, 卵巢囊肿剥除术, 卵巢储备功能

Abstract: Objective To compare the clinical efficacy between the vaginal ovarian cystectomy and the laparoscopic ovarian cystectomy. Methods A total of 104 patients with ovarian cyst hospitalized in our hospital during June 2013-June 2016 were selected and divided into observation group (vaginal ovarian cystectomy, n=55) and control group (laparoscopic ovarian cystectomy, n=49). There were no significant differences in mean age, body mass index (BMI), abdominal surgical history, cyst diameter and cyst type between the two groups. The operation time, blood loss in operation, hospitalization expenses and average hospital stay were observed in the two groups. The ovarian reserve function before and after the operation was also observed. Results The operation time [(46.9±18.4 min)], hospitalization cost [(8 165.3±951.8) yuan] and the average length of hospital stay (4.5±1.9 days) were significantly less in the observation group than those of the control group [(62.3±26.5) min], [(12 543.9±1 464.4) yuan] and [(6.8±2.3) days], (P＜0.05). Before the operation, there were no significant differences in estradiol (E2), follicle stimulating hormone (FSH) / luteinizing (LH), FSH and antral follicle count (AFC) between the two groups. After the operation, the values of FSH/LH (1.4±0.4 vs. 1.8±0.6) and FSH [(9.2±2.9) U/L vs. (13.6±4.3) U/L] were significantly decreased in the observation group than those of the control group. The AFC (7.2±1.6 vs. 6.0±1.3) was significantly more in the observation group than that of the control group (P＜0.05). Conclusion The vaginal ovarian cystectomy is of little damage to ovarian reserve function, which is suitable for women of child- bearing age and conforms to the requirement of "value medicine".

Key words: ovarian cysts, laparoscopy, vaginal surgery, ovarian cystectomy, ovarian reserve