天津医药

天津医药 ›› 2018, Vol. 46 ›› Issue (3): 318-323.doi: 10.11958/20171007

• 综述 • 上一篇    下一篇

反流性食管炎相关功能蛋白表达研究进展

赛红梅，唐艳萍，李蕾   

  1. 1天津中医药大学（邮编300193）；2天津市南开医院
  • 收稿日期:2017-10-09 修回日期:2018-01-22 出版日期:2018-03-15 发布日期:2018-03-23
  • 通讯作者: 唐艳萍 E-mail:cb1699@sina.com

Research progress in expression of functional proteins in reflux esophagitis

SAI Hong-mei, TANG Yan-ping, LI Lei   

  1. 1 Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; 2 Tianjin Nankai Hospital
  • Received:2017-10-09 Revised:2018-01-22 Published:2018-03-15 Online:2018-03-23

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摘要： 反流性食管炎是胃食管反流病的常见类型。其发病机制尚未完全明确，但机体免疫、氧化应激、化学损伤等逐渐成为研究热点。结合目前最新研究，与反流性食管炎相关的功能蛋白的表达为发病机制的研究提供了基础，同时部分蛋白也可作为反流性食管炎向食管腺癌发展过程中的监测指标。现综述近年来有关反流性食管炎发病中相关蛋白的表达及意义的研究进展。

关键词: 食管炎, 反流性, 蛋白表达, 研究进展

Abstract: Reflux esophagitis is a common type of gastroesophageal reflux disease. Its pathogenesis is not completely clear, but the body immunity, oxidative stress and chemical damage have gradually become the research focus. According to the latest research, the expressions of related proteins in reflux esophagitis provide a foundation for its pathogenesis. And some kinds of proteins can be used as monitoring index in the development process from reflux esophagitis to esophageal adenocarcinoma. This article is to review the expression and significance of proteins in reflux esophagitis in recent years.

Key words: esophagitis, reflux, protein expression, research progress