天津医药 ›› 2018, Vol. 46 ›› Issue (5): 484-486.doi: 10.11958/20180401

• 临床研究 • 上一篇    下一篇

冠状动脉旁路移植术前行左锁骨下动脉狭窄筛查及诊治的临床研究

裴晓东1 , 刘建实2, 陈庆良2   

  1. 1 天津医科大学 (邮编300070); 2 天津市胸科医院
  • 收稿日期:2018-03-16 修回日期:2018-04-11 出版日期:2018-05-15 发布日期:2018-05-15
  • 通讯作者: 裴晓东 E-mail:peixiaodongdong@163.com

The clinical research on the screening, diagnosis and treatment of the left subclavian artery stenosis before the coronary artery bypass grafting

PEI Xiao-dong1 , LIU Jian-shi 2, CHEN Qing-liang2   

  1. 1 Tianjin Medical University, Tianjin 300070, China; 2 Tianjin Chest Hospital
  • Received:2018-03-16 Revised:2018-04-11 Published:2018-05-15 Online:2018-05-15
  • Contact: Xiao-Dong PEI E-mail:peixiaodongdong@163.com

摘要: 摘要: 目的 探讨冠状动脉旁路移植术前进行左锁骨下动脉狭窄筛查及诊治的意义和方法。方法 对天津市胸科医院612例冠状动脉旁路移植术患者术前采用无创动脉硬化检测技术筛查合并左锁骨下动脉重度狭窄或闭塞患者, 用电子计算机断层扫描血管造影 (CTA) 明确诊断, 然后行左锁骨下动脉支架成形术, 术后1周行非体外循环冠状动脉旁路移植术, 术中均使用左乳内动脉与前降支吻合。结果 使用无创动脉硬化检测技术筛查出5例左锁骨下动脉狭窄病变患者, 且均得到了CTA确诊。左锁骨下动脉支架成形术成功率为100% (5/5), 术后残余狭窄率均小于 10%, 症状性患者的症状均消失, 双侧上臂收缩压差均小于20 mmHg。使用左乳内动脉与冠状动脉前降支搭桥术中左乳内动脉血流量正常, 术后心绞痛症状均消失, 未发现冠状动脉-锁骨下动脉窃血综合征。围手术期无脑卒中、 心肌梗死及死亡并发症。随访6~12个月, 平均10个月, 无后循环缺血、 上肢缺血、 心肌缺血相关症状, 双侧上臂收缩压差均小于20 mmHg。结论 无创动脉硬化检测技术对锁骨下动脉狭窄的筛查有独到的价值。

关键词: 冠状动脉旁路移植术, 非体外循环, 锁骨下动脉窃血综合征, 血管成形术, 支架, 无创动脉硬化检测

Abstract: Abstract Objective To discuss the meanings and methods of the screening, diagnosis and treatment of the left subclavian artery stenosis before the coronary artery bypass grafting (CABG). Methods A total of 612 patients intend to perform coronary artery bypass grafting in Tianjin Thoracic Hospital, and who were with severe stenosis or occlusion with left subclavian artery were screened by non invasive arteriosclerosis before operation. The diagnosis was confirmed by computerized tomography angiography (CTA), then the stenting angioplasty to the left subclavian artery was performed. The off-pump bypass surgery with the left internal thoracic artery(LITA)- left anterior descending artery (LAD) bypass was performed one week after operation. Results The CTA and digital subtraction angiography (DSA) confirmed the results of the left subclavian stenosis according to the non-invasive artery testing. All the 5 patients were performed with the stenting angioplasty to the left subclavian artery successfully, and the residual stenosis rate was <10%. The clinical symptoms were markedly improved after operations in all symptomatic patients, and the systolic pressure difference was <20 mmHg in two upper extremities. The blood flow was enough in LITA during the LITA-LAD bypass. The angina pectoris was improved after the operation. No coronary-subclavian artery steal phenomenon occurred. Neither stroke, myocardial infraction nor death occurred during perioperative period. All the patients were followed up for a time of 6-12 months, and the average time was about 10 months. No posterior circulation, upper limbs or myocardial ischemia occurred, and the systolic pressure difference was <20 mmHg in two upper extremities. Conclusion The non-invasion testing is of unique value in the screening of the left subclavian artery stenosis.

Key words: coronary artery bypass, off-pump, subclavian steal syndrome, angioplasty, stents, non-invasive arterial sclerosis testing